XBP1, X-box binding protein 1, 7494

N. diseases: 234; N. variants: 6
Disease: Pancreatitis, Chronic ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0149521
Disease: Pancreatitis, Chronic
Pancreatitis, Chronic 		0.030 Biomarker disease BEFREE Finally, we showed that p53 expression could be regulated by the ATF6/XBP1/CHOP axis to promote the development of CP. 31506423 2019
CUI: C0149521
Disease: Pancreatitis, Chronic
Pancreatitis, Chronic 		0.030 AlteredExpression disease BEFREE The unfolded protein response proteins GRP78, ATF6 and XBP1s were found expressed in CP and PDAC peritumoral tissues, but in contrast to AGR2, their expression was switched off during TC and PanIN formation. 27941872 2017
CUI: C0149521
Disease: Pancreatitis, Chronic
Pancreatitis, Chronic 		0.030 Biomarker disease BEFREE We show sustained up-regulation of unfolded protein response components ATF4, CHOP, GRP78, and XBP1 in CP. 25077966 2014