XBP1, X-box binding protein 1, 7494

N. diseases: 234; N. variants: 6
Disease: Aortic aneurysm without mention of rupture NOS ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0340629
Disease: Aortic aneurysm without mention of rupture NOS
Aortic aneurysm without mention of rupture NOS 		0.010 Biomarker disease BEFREE XBP1u, but not XBP1s, was markedly repressed in the aorta during the early onset of aortic aneurysm in both angiotensin II-infused apolipoprotein E knockout (ApoE<sup>-/-</sup>) and CaPO<sub>4</sub> (calcium phosphate)-induced C57BL/6J murine models, in parallel with a decrease in smooth muscle cell contractile apparatus proteins. 29089350 2017