XIST, X inactive specific transcript, 7503

N. diseases: 146; N. variants: 0
Disease: Gastrointestinal carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0151544
Disease: Gastrointestinal carcinoma
Gastrointestinal carcinoma 		0.010 AlteredExpression disease BEFREE Our results showed that expression level of XIST was markedly associated with overall survival (function as oncogene, HR = 0.53, 95% CI: 0.42-0.68, <i>p</i> < 0.00001; function as tumor suppressor, HR = 2.25, 95% CI: 1.15-4.37, <i>p</i> = 0.02), disease free survival (DFS)(HR = 0.45; 95% CI: 0.31-0.67, <i>p</i> < 0.0001), tumor type (digestive system carcinoma, HR = 0.50; 95% CI: 0.37-0.69, <i>p</i> < 0.00001; non-digestive system carcinoma, HR = 0.58; 95% CI: 0.39-0.87, <i>p</i> = 0.008), lymph node metastasis (OR = 0.32, 95% CI: 0.20-0.52, <i>p</i> < 0.00001), distant metastasis (OR = 0.36, 95% CI: 0.22-0.60, <i>p</i> < 0.0001) and tumor stage (OR = 0.43, 95% CI: 0.31-0.60, <i>p</i> < 0.00001). 29568404 2018