XIST, X inactive specific transcript, 7503

N. diseases: 146; N. variants: 0
Disease: Metastatic malignant neoplasm to brain ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0220650
Disease: Metastatic malignant neoplasm to brain
Metastatic malignant neoplasm to brain 		0.010 Biomarker disease BEFREE Furthermore, we screened an FDA-approved drug library and identified fludarabine as a synthetic lethal drug for XIST<sup>low</sup> breast tumor cells and found that fludarabine blocked brain metastasis in our animal model. 30026327 2018