XPNPEP1, X-prolyl aminopeptidase 1, 7511

N. diseases: 20; N. variants: 0
Disease: Adenomatous Polyposis Coli ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0032580
Disease: Adenomatous Polyposis Coli
Adenomatous Polyposis Coli 		0.030 Biomarker disease BEFREE One set of motifs frequently lost in these cancer-associated truncations is the SAMP repeats that mediate interactions between APC and Axin. 26446838 2015
CUI: C0032580
Disease: Adenomatous Polyposis Coli
Adenomatous Polyposis Coli 		0.030 Biomarker disease BEFREE Our data showed that a short domain containing the first SAMP repeat in truncated APC was required to stimulate Axin oligomerisation. 24722208 2014
CUI: C0032580
Disease: Adenomatous Polyposis Coli
Adenomatous Polyposis Coli 		0.030 GeneticVariation disease BEFREE Mammalian APC2, which closely resembles APC in overall domain structure, was functionally analyzed and shown to contain two SAMP domains, both of which are required for binding to conductin. 10021369 1999