XRCC1, X-ray repair cross complementing 1, 7515

N. diseases: 410; N. variants: 39
Disease: Malignant neoplasm of larynx ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007107
Disease: Malignant neoplasm of larynx
Malignant neoplasm of larynx 		0.040 GeneticVariation disease BEFREE Overall, our results found that only AA genotype of the XRCC1 gene Arg399Gln polymorphism under the homozygous model was associated with increased the risk of patients with laryngeal cancer (AA vs. GG: OR=1.29, 95% CI=1.00-1.65, P=0.05). 26898429 2016
CUI: C0007107
Disease: Malignant neoplasm of larynx
Malignant neoplasm of larynx 		0.040 GeneticVariation disease BEFREE In conclusion, the results of our study suggest that the AA genotype and A allele of the XRCC1 Arg280His polymorphism are associated with an increased laryngeal cancer risk in a Chinese population. 27808358 2016
CUI: C0007107
Disease: Malignant neoplasm of larynx
Malignant neoplasm of larynx 		0.040 GeneticVariation disease BEFREE Therefore, we concluded that XRCC1 gene Arg399Gln polymorphism was not associated with laryngeal cancer. 24194393 2014
CUI: C0007107
Disease: Malignant neoplasm of larynx
Malignant neoplasm of larynx 		0.040 GeneticVariation disease BEFREE The results indicated that XRCC1 genetic polymorphisms were associated with larynx cancer in a Chinese population. 24956286 2014