XRCC3, X-ray repair cross complementing 3, 7517

N. diseases: 184; N. variants: 24
Disease: Malignant neoplasm of skin ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007114
Disease: Malignant neoplasm of skin
Malignant neoplasm of skin 		0.330 GeneticVariation disease BEFREE X-ray repair cross-complementing group 1 (XRCC1) and group 3 (XRCC3) polymorphisms are relatively frequent in Caucasian populations and may have implications in skin cancer modulation. 25218703 2014
CUI: C0007114
Disease: Malignant neoplasm of skin
Malignant neoplasm of skin 		0.330 GeneticVariation disease BEFREE Overall, no significant association was observed between XRCC3 C18067T polymorphism and skin cancer risk in any genetic model. 24454720 2014
CUI: C0007114
Disease: Malignant neoplasm of skin
Malignant neoplasm of skin 		0.330 Biomarker disease CTD_human Single nucleotide polymorphisms in DNA repair genes and basal cell carcinoma of skin. 16501254 2006
CUI: C0007114
Disease: Malignant neoplasm of skin
Malignant neoplasm of skin 		0.330 GeneticVariation disease BEFREE We selected 11 haplotype-tagging single nucleotide polymorphisms in three DSB repair genes XRCC2, XRCC3, and LigaseIV and evaluated their associations with skin cancer risk in a nested case-control study within the Nurses' Health Study [219 melanoma, 286 squamous cell carcinoma (SCC), 300 basal cell carcinoma (BCC), and 873 controls]. 15126335 2004
CUI: C0007114
Disease: Malignant neoplasm of skin
Malignant neoplasm of skin 		0.330 Biomarker disease CTD_human A variant within the DNA repair gene XRCC3 is associated with the development of melanoma skin cancer. 11059748 2000