XRCC3, X-ray repair cross complementing 3, 7517

N. diseases: 184; N. variants: 24
Disease: melanoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0025202
Disease: melanoma
melanoma 		0.360 GeneticVariation disease BEFREE This meta-analysis suggested that the XRCC3 rs861539 polymorphism was not a risk factor for cutaneous melanoma susceptibility. 26922354 2016
CUI: C0025202
Disease: melanoma
melanoma 		0.360 GeneticVariation disease BEFREE The present meta-analysis demonstrates that XRCC3 C18067T polymorphism was not associated with risk of cutaneous melanoma but contributed a decreased risk to both basal cell carcinoma and squamous cell carcinoma. 24454720 2014
CUI: C0025202
Disease: melanoma
melanoma 		0.360 GeneticVariation disease BEFREE Data analyses showed that none of the polymorphisms except T241M XRCC3 was associated with an increased risk for cutaneous melanoma. 20601096 2010
CUI: C0025202
Disease: melanoma
melanoma 		0.360 GeneticVariation disease BEFREE We found no evidence therefore that the T allele of this XRCC3 polymorphism is indicative of susceptibility to melanoma. 15009726 2004
CUI: C0025202
Disease: melanoma
melanoma 		0.360 GeneticVariation disease LHGDN DNA repair gene XRCC3 241Met variant is not associated with risk of cutaneous malignant melanoma. 12376526 2002
CUI: C0025202
Disease: melanoma
melanoma 		0.360 GeneticVariation disease BEFREE We found the presence of a T allele in exon 7 (position 18067) of the XRCC3 gene was significantly associated with melanoma development (P = 0.004; odds ratio, 2.36; relative risk, 1.74). 11059748 2000
CUI: C0025202
Disease: melanoma
melanoma 		0.360 Biomarker disease CTD_human We found the presence of a T allele in exon 7 (position 18067) of the XRCC3 gene was significantly associated with melanoma development (P = 0.004; odds ratio, 2.36; relative risk, 1.74). 11059748 2000