YY1, YY1 transcription factor, 7528

N. diseases: 245; N. variants: 10
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0023418
Disease: leukemia
leukemia
0.040 Biomarker disease BEFREE Leukaemia cell DNA showed rearrangement of both immunoglobulin heavy chain and T-cell receptor delta genes. 1907927 1991
CUI: C0023418
Disease: leukemia
leukemia
0.040 Biomarker disease BEFREE We have analyzed the configuration of the immunoglobulin heavy (IgH) chain gene and the T cell receptor (TCR) chain (beta, gamma, and delta) genes in a group of 22 leukemia patients with the Philadelphia (Ph) chromosome. 2143795 1990
CUI: C0023418
Disease: leukemia
leukemia
0.040 GeneticVariation disease BEFREE The comparison of morphological, phenotypical, and molecular findings from these cases with those from control acute myeloid leukemias whose TCR delta genes were in germline configuration show that TCR delta rearrangements occur predominantly in immature leukemia exhibiting extensive lineage infidelity. 2137546 1990
CUI: C0023418
Disease: leukemia
leukemia
0.040 Biomarker disease BEFREE Because the TCR delta gene has been cloned only recently, no comparable information exists with respect to this in human leukemias. 2492834 1989