Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0338656
Disease: Impaired cognition
Impaired cognition
0.040 Biomarker disease BEFREE Oleanolic acid protects against cognitive decline and neuroinflammation-mediated neurotoxicity by blocking secretory phospholipase A2 IIA-activated calcium signals. 29747052 2018
CUI: C0338656
Disease: Impaired cognition
Impaired cognition
0.040 Biomarker disease BEFREE In AD model mice (3xTg-AD mice), bvPLA2 administration significantly ameliorated cognitive deficits and reduced Aβ burdens in the brains of Aβ-vaccinated 3xTg-AD mice. 30478329 2018
CUI: C0338656
Disease: Impaired cognition
Impaired cognition
0.040 Biomarker disease BEFREE Phospholipase A2 reduction ameliorates cognitive deficits in a mouse model of Alzheimer's disease. 18931664 2008
CUI: C0338656
Disease: Impaired cognition
Impaired cognition
0.040 AlteredExpression disease BEFREE A stronger overexpression for 14-3-3 zeta gene is demonstrated in the affected temporal cortex of cases with cognitive impairment than in cases with normal mental status. 15234461 2004