Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.030 Biomarker disease BEFREE Recently, clinical studies suggested sterol regulatory element-binding protein (SREBP) as a susceptibility gene in patients with schizophrenia. 30430717 2019
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.030 Biomarker disease BEFREE Here we review the evidence for the involvement of SREBF1 and SREBF2 as genetic risk factors in schizophrenia and discuss the role of myelination and SREBP-mediated lipid biosynthesis in the etiology, pathophysiology and drug treatment of schizophrenia. 27492885 2017
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.030 Biomarker disease BEFREE This finding strengthens the hypothesis that SREBP-controlled cholesterol biosynthesis is involved in the etiology of schizophrenia. 18936756 2010