Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2936179
Disease: Obesity, Visceral
Obesity, Visceral
0.030 Biomarker phenotype BEFREE The differences in hepatic gene expression and peroxisomal protein patterns were surprisingly small between the control and alb-SREBP-1a mice, although the latter develop a severe phenotype with visceral obesity and fatty liver. 29587401 2018
CUI: C2936179
Disease: Obesity, Visceral
Obesity, Visceral
0.030 PosttranslationalModification phenotype BEFREE Preventing phosphorylation of sterol regulatory element-binding protein 1a by MAP-kinases protects mice from fatty liver and visceral obesity. 22384276 2012
CUI: C2936179
Disease: Obesity, Visceral
Obesity, Visceral
0.030 Biomarker phenotype BEFREE In conclusion, the alb-SREBP-1c mouse model allowed the elucidation of the systemic impact of SREBP-1c as a central regulator of lipid metabolism in vivo and also demonstrated that the liver is a more active player in metabolic diseases such as visceral obesity and insulin resistance. 22363740 2012