Disease: Fatty Liver Disease ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4529962
Disease: Fatty Liver Disease
Fatty Liver Disease 		0.030 Biomarker disease BEFREE Therefore, this study for the first time explored the preventive effect of trans-chalcone on NASH through the modulation of sterol regulatory element binding protein (SREBP)-1c, SREBP-2, hepatic fatty acid synthesis (FAS) enzyme, proliferator-activated receptor (PPAR)-α, and PPAR-γ2 levels, which are involved in hepatic lipid metabolism. 30551380 2019
CUI: C4529962
Disease: Fatty Liver Disease
Fatty Liver Disease 		0.030 AlteredExpression disease BEFREE The beneficial role of melatonin in dietary induced NAFLD/NASH in mice was related to reduced expression of microRNA-34a-5p and sterol regulatory element-binding protein (SREBP1) but only in the presence of full SIRT1 availability. 31500354 2019
CUI: C4529962
Disease: Fatty Liver Disease
Fatty Liver Disease 		0.030 AlteredExpression disease BEFREE Down-regulation of SREBP-1c and lipogenic enzymes may be associated with the development of burned-out NASH. 20655124 2010