CA9, carbonic anhydrase 9, 768

N. diseases: 226; N. variants: 4
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.100 Biomarker disease BEFREE Survival analyses were performed by Kaplan⁻Meier and Cox's regression analysis to estimate the prognostic effect of CA9/CAIX in OSCC patients. 30654595 2019
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.100 GeneticVariation disease BEFREE In conclusion, CA9 SNP rs1048638 and haplotype A1AA are associated with the susceptibility of cervical invasive squamous cell carcinoma for Taiwanese women. 29725249 2018
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.100 AlteredExpression disease BEFREE Impact of tumoral carbonic anhydrase IX and Ki-67 expression on survival in oral squamous cell carcinoma patients. 29098033 2017
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.100 AlteredExpression disease BEFREE Clinically relevant HIF-1α-dependent metabolic reprogramming in oropharyngeal squamous cell carcinomas includes coordinated activation of CAIX and the miR-210/ISCU signaling axis, but not MCT1 and MCT4 upregulation. 28099149 2017
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.100 AlteredExpression disease BEFREE In conclusion, our study showed that the expression of CAIX in OSCC samples can predict the progression of OSCC and survival of OSCC patients in Taiwan. 26130414 2015
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.100 AlteredExpression disease BEFREE Increased expression of carbonic anhydrase IX in oral submucous fibrosis and oral squamous cell carcinoma. 24695043 2014
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.100 AlteredExpression disease BEFREE Expression of CA IX in dysplasia adjacent to surgical resection margins of oral squamous cell carcinoma. 23957700 2014
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.100 AlteredExpression disease BEFREE Expression of CA-IX is associated with advanced stage tumors and poor survival in oral squamous cell carcinoma patients. 22486898 2012
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.100 AlteredExpression disease LHGDN Expression of carbonic anhydrase 9, a potential intrinsic marker of hypoxia, is associated with poor prognosis in oesophageal squamous cell carcinoma. 18841153 2008
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.100 Biomarker disease LHGDN Expression of carbonic anhydrase IX is associated with postoperative recurrence and poor prognosis in surgically treated oral squamous cell carcinoma. 18440050 2008
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.100 Biomarker disease LHGDN Three-gene expression signature predicts survival in early-stage squamous cell carcinoma of the lung. 18676750 2008
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.100 Biomarker disease LHGDN The prognostic value of the hypoxia markers CA IX and GLUT 1 and the cytokines VEGF and IL 6 in head and neck squamous cell carcinoma treated by radiotherapy +/- chemotherapy. 15847702 2005
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.100 AlteredExpression disease LHGDN Expression of CA9, IdUrd labeling, and colocalization between IdUrd and CA9 was examined by immunohistochemistry in biopsies of head and neck squamous cell carcinomas. 15671533 2005