ZNF143, zinc finger protein 143, 7702

N. diseases: 39; N. variants: 2
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.050 AlteredExpression group BEFREE Here, we investigated whether ZNF143 expression affects the tumour microenvironment and tumour progression by screening molecules secreted by colon cancer cells stably expressing short-hairpin RNAs against ZNF143 or control RNAs. 30933430 2019
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.050 AlteredExpression group BEFREE Moreover, ZNF143 participated in miR-590-3p-induced tumor-suppressive activity on glioma cells. 31186064 2019
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.050 Biomarker group BEFREE The present study revealed that the inhibition of ZNF143 activity by small molecules induced tumor regression in vitro and in vivo; therefore, ZNF143 is a promising target of cancer therapeutics. 28192620 2017
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.050 AlteredExpression group BEFREE Zinc finger protein 143 expression is closely related to tumor malignancy via regulating cell motility in breast cancer. 29065970 2017
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.050 Biomarker group BEFREE Role of ZNF143 in tumor growth through transcriptional regulation of DNA replication and cell-cycle-associated genes. 20860770 2010