Disease: Alzheimer's Disease ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.050 Biomarker disease BEFREE NEP immunolabeling is reduced within cerebral blood vessels of Alzheimer's disease (AD) patients with cerebral amyloid angiopathy (CAA). 21382117 2011
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.050 Biomarker disease BEFREE NEP-like endopeptidases and Alzheimer's disease [corrected]. 20088804 2010
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.050 GeneticVariation disease BEFREE Combined risk effects of IDE and NEP gene variants on Alzheimer disease. 19864659 2009
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.050 AlteredExpression disease BEFREE Our results unequivocally indicate significance of CSF-NEP as a biochemical indicator to pursue a pathological process that involves decreased neprilysin activity and A beta-induced synaptic toxicity, and the support the potential benefits of neprilysin up-regulation in ameliorating neuropathology in prodromal and early AD. 15929037 2005
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.050 AlteredExpression disease BEFREE NEP can degrade amyloid beta peptides, and its mRNA and protein levels are known to be reduced in the brains of patients with Alzheimer's disease (AD), making the NEP gene a substantial candidate for an AD risk factor. 14739539 2004