Disease: Alport Syndrome ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1567741
Disease: Alport Syndrome
Alport Syndrome 		0.020 Biomarker disease BEFREE Compound 2.45 preserves renal function and reduces tissue damage in Col4a3<sup>-/-</sup> mice (the preclinical mouse model of Alport syndrome) when employing a therapeutic dosing regime, indicating the real therapeutic value of selectively inhibiting DDR1 phosphorylation in vivo. 30452219 2019
CUI: C1567741
Disease: Alport Syndrome
Alport Syndrome 		0.020 Biomarker disease BEFREE The present study evaluates the role of Discoidin Domain Receptor 1 (DDR1) in cell-matrix interaction involved in pathogenesis of Alport syndrome including renal inflammation and fibrosis. 20307660 2010