FZD5, frizzled class receptor 5, 7855

N. diseases: 82; N. variants: 0
Disease: Rhabdoid Tumor of the Kidney ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0854917
Disease: Rhabdoid Tumor of the Kidney
Rhabdoid Tumor of the Kidney 		0.010 Biomarker disease BEFREE Canonical WNT signaling through Frizzled and LRP5/6 receptors is transduced to the WNT/β-catenin and WNT/stabilization of proteins (STOP) signaling cascades to regulate cell fate and proliferation, whereas non-canonical WNT signaling through Frizzled or ROR receptors is transduced to the WNT/planar cell polarity (PCP), WNT/G protein-coupled receptor (GPCR) and WNT/receptor tyrosine kinase (RTK) signaling cascades to regulate cytoskeletal dynamics and directional cell movement. 28731148 2017