Cardiovascular Diseases
|
0.200 |
GeneticVariation
|
group |
BEFREE |
Association between FTO gene polymorphisms and HDL cholesterol concentration may cause higher risk of cardiovascular disease in patients with acromegaly.
|
28913579 |
2018 |
Cardiovascular Diseases
|
0.200 |
GeneticVariation
|
group |
BEFREE |
This study aimed to confirm the effect of common putative CVD-associated gene variants (FTO rs17817449, KIF6 rs20455, 9p21 rs10757274 and 2q36.3 rs2943634) on CVD manifestation, and determine whether this effect differs between younger (< 50 years) and older CVD patients.
|
26772723 |
2016 |
Cardiovascular Diseases
|
0.200 |
Biomarker
|
group |
BEFREE |
The FTO gene has recently become one of the most extensively investigated genes associated with body mass and has been shown to play a role in cardiovascular diseases as well.
|
26878843 |
2016 |
Cardiovascular Diseases
|
0.200 |
GeneticVariation
|
group |
BEFREE |
The AA genotype of FTO rs9939609 seems to be associated with a higher risk of CVD, and this phenomenon seems to be independent of the traditional risk factors for atherosclerosis.
|
26555680 |
2015 |
Cardiovascular Diseases
|
0.200 |
Biomarker
|
group |
BEFREE |
Therefore, we ascertained whether FTO is associated with aortic valve stenosis (AVS), one of the most frequent cardiovascular diseases in the Western world.
|
26431034 |
2015 |
Cardiovascular Diseases
|
0.200 |
GeneticVariation
|
group |
BEFREE |
The aim of this study was to evaluate the prevalence of cardiovascular disease risk factors as well as the fat mass and obesity associated (FTO) gene rs9939609 variant in a large group of children with T1DM of the same ethnic-Polish origin.
|
25184161 |
2014 |
Cardiovascular Diseases
|
0.200 |
GeneticVariation
|
group |
BEFREE |
Variants in the fat mass- and obesity-associated gene (FTO) predisposing to obesity and diabetes mellitus have also been associated with cardiovascular disease.
|
24622111 |
2014 |
Cardiovascular Diseases
|
0.200 |
GeneticVariation
|
group |
BEFREE |
At least in white persons, platelet count seems not to be a link between the FTO variation and risk of cardiovascular disease.
|
23254338 |
2013 |
Cardiovascular Diseases
|
0.200 |
Biomarker
|
group |
BEFREE |
We assessed the association of 52 FTO polymorphisms, spanning the whole gene, with obesity and estimated the influence of these polymorphisms on anthropometric, clinical and metabolic parameters as well as inflammation and cardiovascular disease (CVD) risk biomarkers among Spanish children.
|
24289790 |
2013 |
Cardiovascular Diseases
|
0.200 |
GeneticVariation
|
group |
BEFREE |
The present meta-analysis confirmed the significant association of the rs9939609 variant in the FTO gene with CVD risk, which was independent of BMI and other conventional CVD risk factors.
|
23977173 |
2013 |
Cardiovascular Diseases
|
0.200 |
GeneticVariation
|
group |
BEFREE |
Reduced memory in fat mass and obesity-associated allele carriers among older adults with cardiovascular disease.
|
23551410 |
2013 |
Cardiovascular Diseases
|
0.200 |
GeneticVariation
|
group |
BEFREE |
The association of the FTO rs9939609 polymorphism with obesity and metabolic risk factors for cardiovascular diseases in Polish children.
|
22791637 |
2012 |
Cardiovascular Diseases
|
0.200 |
GeneticVariation
|
group |
BEFREE |
Cox-regression models were used to assess the relative risks of developing AD and dementia (DSM-III-R criteria) according to FTO genotypes (rs9939609), taking into account APOE, physical inactivity, BMI, diabetes, and cardiovascular disease (CVD).
|
21098976 |
2011 |
Cardiovascular Diseases
|
0.200 |
GeneticVariation
|
group |
BEFREE |
We investigated whether the SNP rs9939609 (T/A) of the FTO is associated with risk factors of cardiovascular diseases (CVD), including serum levels of C - reactive protein (CRP), the chemokine RANTES (Regulated on Activation, Normal T Cell Expressed and Secreted; CCL5), and serum and lipoprotein lipids in the Finnish Diabetes Prevention Study (DPS).
|
20400278 |
2011 |
Cardiovascular Diseases
|
0.200 |
Biomarker
|
group |
BEFREE |
We found a significant association of FTO with CVD only among less-active (≤8.8 metabolic equivalent-h/wk) women (HR 1.19, 95% CI 1.02-1.38) in multivariate analyses that included BMI.
|
21146673 |
2010 |
Cardiovascular Diseases
|
0.200 |
GeneticVariation
|
group |
BEFREE |
Four polymorphisms (rs9939609 [FTO], rs11084753 [KCTD15], rs10838738 [MTCH2], and rs10938397 [GNPDA2]) showed nominally significant associations with CVD.
|
19910641 |
2010 |
Cardiovascular Diseases
|
0.200 |
GeneticVariation
|
group |
BEFREE |
To determine if FTO variants are associated with BMI in Old Order Amish (OOA) individuals, and to further determine whether the detrimental associations of FTO gene variants can be lessened by increased physical activity, a total of 704 healthy OOA adults were selected from the Heredity and Phenotype Intervention (HAPI) Heart Study, an investigation of gene x environment interactions in cardiovascular disease, for whom objective quantified physical activity measurements were available and for whom 92 single-nucleotide polymorphisms (SNPs) in FTO were genotyped.
|
18779467 |
2008 |