DERL1, derlin 1, 79139

N. diseases: 85; N. variants: 0
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
0.030 AlteredExpression phenotype BEFREE Derlin-1 is overexpressed in various types of solid tumors and has an important function in cancer progression. 27977784 2016
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
0.030 Biomarker phenotype BEFREE Previous studies indicated a role of Derlin-1 in human cancers; however, its expression pattern in non-small cell lung cancer (NSCLC) and the molecular mechanism of Derlin-1 on cancer progression have not been characterized. 23306155 2013
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
0.030 GeneticVariation phenotype BEFREE This makes the der(1;16)(q10;p10) and other alterations of the 16q arm an early alteration of tumor progression, possibly related to the loss of expression of E-cadherin, whose gene is mapped on the 16q arm. 9824202 1998