Disease: Acute Chest Syndrome ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0742343
Disease: Acute Chest Syndrome
Acute Chest Syndrome 		0.050 Biomarker disease BEFREE Certain miRNAs, for instance, miR-1, miR-133a/b, miR-208a/b, and miR-499a, strongly increase in the serum or plasma of patients with acute cardiac ischemia, making them as cardio-specific miRNAs and prospective biomarkers in ACS. 31772848 2019
CUI: C0742343
Disease: Acute Chest Syndrome
Acute Chest Syndrome 		0.050 Biomarker disease BEFREE Two miRNAs (hsa-miR-29 and hsa-miR-1) and three TFs (NFIC, NFKB1 and RELA) were critical genes involved in pathological process of ACS. 31550669 2019
CUI: C0742343
Disease: Acute Chest Syndrome
Acute Chest Syndrome 		0.050 Biomarker disease BEFREE Looking at differential markers between cardiovascular disease revealed miR-1, miR-208a and miR-133a to distinguish ACS and CAD to HF. 28666417 2017
CUI: C0742343
Disease: Acute Chest Syndrome
Acute Chest Syndrome 		0.050 Biomarker disease BEFREE In particular, miR-133a/b (5 studies), miR-208a/b (6 studies), and miR-499 (7 studies) were well studied and found to be significant diagnostic and/or prognostic markers across different cardiovascular disease progression stages. miR-1 and miR-145b are potential biomarkers of ACS; miR-1 with higher sensitivity for all acute myocardial infarction (AMI), and miR-145 for STEMI and worse outcome of AMI. 27357636 2016
CUI: C0742343
Disease: Acute Chest Syndrome
Acute Chest Syndrome 		0.050 Biomarker disease BEFREE Cardio-enriched miRNAs (miR-1, miR-208b and miR-499-5p) were measured using real time PCR in plasma samples from 424 patients with suspected ACS treated in a coronary care unit. miRNAs were assessed for discrimination of a clinical diagnosis of myocardial infarction and for association with 30-day mortality and diagnosis of heart failure. 23448306 2013