Malignant mesothelioma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
In various MM cell lines and regardless of calretinin expression levels, blocking of FAK signaling activated the Wnt signaling pathway and <i>vice versa</i>.
|
31671889 |
2019 |
Malignant mesothelioma
|
0.400 |
Biomarker
|
disease |
BEFREE |
When the detection of TNXB was combined with that of calretinin, 83.3% of MM cases were detected.
|
30711938 |
2019 |
Malignant mesothelioma
|
0.400 |
Biomarker
|
disease |
BEFREE |
This is the first prospective cohort study to evaluate a detection of MM by calretinin and its combination with mesothelin up to about a year before clinical diagnosis.
|
30254313 |
2018 |
Malignant mesothelioma
|
0.400 |
Biomarker
|
disease |
BEFREE |
The mechanisms of calretinin regulation, as well as its distinct function in MM are still poorly understood.
|
29699512 |
2018 |
Malignant mesothelioma
|
0.400 |
Biomarker
|
disease |
BEFREE |
Finally, CR downregulation via a lentiviral shRNA against CR (<i>CALB2</i>) resulted in a significantly reduced tumor formation <i>in vivo</i> in an orthotopic xenograft mouse model based on peritoneal MM cell injection.
|
30555628 |
2018 |
Malignant mesothelioma
|
0.400 |
Biomarker
|
disease |
BEFREE |
Calretinin Functions in Malignant Mesothelioma Cells Cannot Be Replaced by the Closely Related Ca<sup>2+</sup>-Binding Proteins Calbindin-D28k and Parvalbumin.
|
30545133 |
2018 |
Malignant mesothelioma
|
0.400 |
Biomarker
|
disease |
BEFREE |
Molecular markers like calretinin and mesothelin are promising tools to improve and supplement the diagnosis of MM and warrant further validation in a prospective study.
|
28558669 |
2017 |
Malignant mesothelioma
|
0.400 |
Biomarker
|
disease |
BEFREE |
Assessment of potential predictors of calretinin and mesothelin to improve the diagnostic performance to detect malignant mesothelioma: results from a population-based cohort study.
|
29025836 |
2017 |
Malignant mesothelioma
|
0.400 |
Biomarker
|
disease |
BEFREE |
These results demonstrate that downregulation of CR had a strong effect on the viability of MM cells and that CR is essential for cells derived from MM.
|
23595591 |
2013 |
Malignant mesothelioma
|
0.400 |
Biomarker
|
disease |
CTD_human |
Immunohistochemical analysis for epithelial membrane antigen, calretinin, vimentin, β-catenin, melan-A, glucose transporter-1, cytokeratin CAM5.2, Wilms tumor antigen-1, D2-40, CD146, progesterone receptor, estrogen receptor, and cytokeratin 5/6 was indicative of malignant mesothelioma.
|
22784439 |
2013 |
Malignant mesothelioma
|
0.400 |
Biomarker
|
disease |
BEFREE |
Calretinin was positive in 100% of MMs, in none of the metastatic carcinomas, and in 94.9% of negative effusions.
|
18306350 |
2008 |
Malignant mesothelioma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Both cell lines showed the immunologic profile characteristic for MM (i.e., expression of cytokeratin, CK18, calretinin, and vimentin in both phenotypes).
|
17574962 |
2007 |
Malignant mesothelioma
|
0.400 |
Biomarker
|
disease |
BEFREE |
Although calretinin is a sensitive IHC marker for MM, it is not specific since it stained 30% of PA. Conversely, to differentiate between MM and PSCC, p63 and WT-1 are the best available markers.
|
17115439 |
2006 |
Malignant mesothelioma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
In contrast, the "AP2-like" sequence does not play such a role in regulation of the CR gene transcription in adenocarcinoma and mesothelioma cancer cells.
|
15093134 |
2004 |
Malignant mesothelioma
|
0.400 |
Biomarker
|
disease |
BEFREE |
The calretinin promoter seems to be a promising candidate as a specific and efficient promoter in malignant mesothelioma.
|
11396148 |
2001 |
Peritoneal Neoplasms
|
0.300 |
Biomarker
|
group |
CTD_human |
Two cases of malignant peritoneal mesothelioma without asbestos exposure: cytologic and immunohistochemical features.
|
22784439 |
2013 |
Carcinomatosis of peritoneal cavity
|
0.300 |
Biomarker
|
disease |
CTD_human |
Two cases of malignant peritoneal mesothelioma without asbestos exposure: cytologic and immunohistochemical features.
|
22784439 |
2013 |
Uveitis
|
0.300 |
Biomarker
|
disease |
CTD_human |
Mitochondrial proteomics in experimental autoimmune uveitis oxidative stress.
|
19578012 |
2009 |
AMYOTROPHIC LATERAL SCLEROSIS 1
|
0.300 |
Biomarker
|
disease |
CTD_human |
Differential expression of inflammation- and apoptosis-related genes in spinal cords of a mutant SOD1 transgenic mouse model of familial amyotrophic lateral sclerosis.
|
11796754 |
2002 |
Amyotrophic Lateral Sclerosis, Sporadic
|
0.300 |
Biomarker
|
disease |
CTD_human |
Differential expression of inflammation- and apoptosis-related genes in spinal cords of a mutant SOD1 transgenic mouse model of familial amyotrophic lateral sclerosis.
|
11796754 |
2002 |
Amyotrophic Lateral Sclerosis, Familial
|
0.300 |
Biomarker
|
disease |
CTD_human |
Differential expression of inflammation- and apoptosis-related genes in spinal cords of a mutant SOD1 transgenic mouse model of familial amyotrophic lateral sclerosis.
|
11796754 |
2002 |
Schizophrenia
|
0.130 |
Biomarker
|
disease |
BEFREE |
<b>Aim:</b> The authors aimed to study cognitive-enhancement- and neuroprotective-effects of Brahmi on novel object recognition memory and GABAergic neuronal density, defined by the presence of calcium binding proteins (CBPs; calbindin (CB), parvalbumin (PV), and calretinin (CR)) in a sub-chronic (2 mg/kg, Bid, ip) phencyclidine (PCP) rat model of schizophrenia.
|
31118643 |
2019 |
Schizophrenia
|
0.130 |
GeneticVariation
|
disease |
BEFREE |
However, ErbB4 is also present in calretinin interneurons, which are not affected in schizophrenia.
|
26337038 |
2016 |
Schizophrenia
|
0.130 |
GeneticVariation
|
disease |
GWASCAT |
Genome-wide association study of schizophrenia in Ashkenazi Jews.
|
26198764 |
2015 |
Schizophrenia
|
0.130 |
AlteredExpression
|
disease |
BEFREE |
In contrast, the same measures of CR mRNA expression were not altered in schizophrenia.
|
12867516 |
2003 |