|
Hirschsprung Disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
The gradients of calretinin-stained pixel count increase per distance from the beginning of TZ (slope) for TCA were not significantly different from those for the conventional HD group.
|
31387515 |
2020 |
|
Hirschsprung Disease
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
On fluorescence microscopy, PGP 9.5, nNOS, and calretinin were significantly lower in the IAS of HD-mice than in C-mice (p < 0.05, respectively), while there were no significant differences between HD-mice and C-mice for S100, VIP, or TH.
|
30413921 |
2019 |
|
Hirschsprung Disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
The density and distribution of intramuscular neuronal nitric oxide synthase (nNOS)- and mucosal calretinin-immunoreactive nerves were evaluated proximal and distal to the anastomosis in redo resection specimens after pull-through surgery for Hirschsprung disease.
|
30915893 |
2019 |
|
Hirschsprung Disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
ChT IHC was useful in unusual scenarios in which calretinin (CR) IHC failed to correctly identify patients with HSCR.
|
28649946 |
2019 |
|
Hirschsprung Disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
Calretinin immunostain was performed on 15 HD pull-through specimens, and multiple images were captured from the proximal aganglionic zone, TZ, and probable normal zone (NZ).
|
29304518 |
2019 |
|
Hirschsprung Disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
At our institution, calretinin immunohistochemistry (CAL) is frequently requested by clinicians on rectal mucosal biopsies (RMBs) taken during colonoscopy in older children in whom suspicion for HD is low.
|
28508695 |
2019 |
|
Hirschsprung Disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
A significant difference between AM- and non-AM-affected tissues was found for calretinin (AM 0.55% vs. non-AM 1.44%) and MAP2 (AM 0.004% vs. non-AM 0.07%) staining measurements and software-based evaluations.
|
30175382 |
2019 |
|
Hirschsprung Disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
Samples, stained with H&E and often acetylcholinesterase and/or calretinin, were categorized as "histologically" positive, negative, or inconclusive for aganglionosis.
|
27755344 |
2017 |
|
Hirschsprung Disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
Rectal suction biopsy with calretinin immunohistochemistry in patients suspected with residual aganglionosis after operation for Hirschsprung disease.
|
28341231 |
2017 |
|
Hirschsprung Disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
To assess the diagnostic role of calretinin immunostaining in HD in comparison to neuron-specific enolase.
|
28139502 |
2017 |
|
Hirschsprung Disease
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
The objectives of the current investigation were to evaluate the concordance of the results obtained by HE staining and the calretinin method with acetylcholinesterase (AChE) activity in fragments of mucosa and submucosa in the diagnosis of HD.
|
29212517 |
2017 |
|
Hirschsprung Disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
Unequivocal calretinin hypoinnervation was limited to the distal 2 cm, substantiating the warning of Kapur that small numbers of CRir nerves in the LP do not exclude a diagnosis of vsHD.
|
26230373 |
2016 |