Hyperalgesia
|
0.540 |
Biomarker
|
phenotype |
BEFREE |
TRPV1 contributes to peripheral sensitization and hyperalgesia, in part, <i>via</i> triggering the release of proinflammatory peptides, such as calcitonin gene-related peptide (CGRP), both locally and at the dorsal horn of the spinal cord.
|
31551772 |
2019 |
Hyperalgesia
|
0.540 |
AlteredExpression
|
phenotype |
BEFREE |
Nevertheless, ghrelin modulated nitroglycerin-triggered changes in transient receptor potential vanilloid-1 and calcitonin gene-related peptide expression, and mitigated nitroglycerin-induced hyperalgesia.
|
29237283 |
2018 |
Hyperalgesia
|
0.540 |
Biomarker
|
phenotype |
BEFREE |
Our study hypothesis is to evaluate the preventive value of epidural calcitonin on postoperative pain, grade of phantom pain, and the development of allodynia and hyperalgesia in patients undergoing lower limb amputation.
|
28100669 |
2017 |
Hyperalgesia
|
0.540 |
Biomarker
|
phenotype |
CTD_human |
Resveratrol suppresses glial activation and alleviates trigeminal neuralgia via activation of AMPK.
|
27093858 |
2016 |
Hyperalgesia
|
0.540 |
Therapeutic
|
phenotype |
CTD_human |
Resveratrol suppresses glial activation and alleviates trigeminal neuralgia via activation of AMPK.
|
27093858 |
2016 |
Hyperalgesia
|
0.540 |
Biomarker
|
phenotype |
RGD |
Up-regulation of dorsal root ganglia BDNF and trkB receptor in inflammatory pain: an in vivo and in vitro study.
|
21958434 |
2011 |
Hyperalgesia
|
0.540 |
Therapeutic
|
phenotype |
CTD_human |
Involvement of substance P, CGRP and histamine in the hyperalgesia and cytokine upregulation induced by intraplantar injection of capsaicin in rats.
|
15265675 |
2004 |
Hyperalgesia
|
0.540 |
Biomarker
|
phenotype |
BEFREE |
PAR2 activation also potentiated capsaicin-induced release of substance P and calcitonin gene-related peptide from superfused segments of the dorsal horn of the spinal cord, where they mediate hyperalgesia.
|
15128844 |
2004 |
Hyperalgesia
|
0.540 |
Biomarker
|
phenotype |
CTD_human |
Involvement of substance P, CGRP and histamine in the hyperalgesia and cytokine upregulation induced by intraplantar injection of capsaicin in rats.
|
15265675 |
2004 |
Hyperalgesia
|
0.540 |
Therapeutic
|
phenotype |
CTD_human |
The role of calcitonin gene-related peptide (CGRP) in the generation and maintenance of mechanical allodynia and hyperalgesia in rats after intradermal injection of capsaicin.
|
12855330 |
2003 |
Hyperalgesia
|
0.540 |
Biomarker
|
phenotype |
CTD_human |
The role of calcitonin gene-related peptide (CGRP) in the generation and maintenance of mechanical allodynia and hyperalgesia in rats after intradermal injection of capsaicin.
|
12855330 |
2003 |
Hyperalgesia
|
0.540 |
Therapeutic
|
phenotype |
CTD_human |
Pharmacological sensitivity and gene expression analysis of the tibial nerve injury model of neuropathic pain.
|
12787826 |
2003 |
Hyperalgesia
|
0.540 |
Biomarker
|
phenotype |
CTD_human |
Pharmacological sensitivity and gene expression analysis of the tibial nerve injury model of neuropathic pain.
|
12787826 |
2003 |