Septicemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
According to our results the IL-18 is a biomarker better differentiating sepsis and septic shock status than PCT, CRP and WBC but with no prognostic impact.
|
31003186 |
2019 |
Septicemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
Therefore, daily PCT measurement should not be used to predict mortality for patients with cancer and sepsis.
|
31284812 |
2019 |
Septicemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
The aim of this study is to evaluate the diagnostic reliability of serum PCT in the diagnosis of sepsis in frail elderly patients.
|
30132205 |
2019 |
Septicemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
A retrospective analysis of PCT and MR-proADM on 571 consecutive patients with sepsis diagnosis was performed.
|
31574301 |
2019 |
Septicemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
Concentrations of these biomarkers in function of sepsis severity (sepsis n = 94 and septic shock n = 21) and outcome (lethal n = 40, recovery n = 75) were tested, as well as correlations with APACHE II and SOFA scores, immunoglobulins, complement, PCT and CRP concentrations.
|
30142533 |
2018 |
Septicemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
In sum activation of TRPV1 by 20-HETE leads to the release of CGRP, which protects the heart against the cardiac dysfunction in endotoxemia and identifies both TRPV1 and CGRP receptors as potential therapeutic targets in endotoxemia.-Chen, J., Hamers, A. J. P., Finsterbusch, M., Massimo, G., Zafar, M., Corder, R., Colas, R. A., Dalli, J., Thiemermann, C., Ahluwalia, A. Endogenously generated arachidonate-derived ligands for TRPV1 induce cardiac protection in sepsis.
|
29465314 |
2018 |
Septicemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
Compared with the non-sepsis group, the sepsis group demonstrated significant increases in PCT but not in WBC or CRP.
|
29968788 |
2018 |
Septicemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
We recruited SIRS (n = 33) and sepsis (n = 89) patients from electronic medical records (EMR) according to whether data on PCT, CRP, interleukin (IL)-1β, IL-2, IL-4, IL-5, IL-6, IL-9, IL-10, IL-12p70, IL-13, IL-17, IL-22, TNF-α, and IFN-γ levels were available.
|
30547887 |
2018 |
Septicemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
T-lymphocyte subsets were detected by flow cytometer, the levels of tumor necrosis factor-α, interleukin-1 and calcitonin were determined by double-antibody immunoluminometric assay, and the effect of vitamin D on the above indicators in the treatment of sepsis was observed.
|
30116318 |
2018 |
Septicemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
Repeated measurements of the procalcitonin (PCT) biomarker are typically used for early detection and follow up of bacterial infections and sepsis, but those PCT measurements are costly.
|
26476896 |
2018 |
Septicemia
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Research on the diagnostic effect of PCT level in serum on patients with sepsis due to different pathogenic causes.
|
30024613 |
2018 |
Septicemia
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
In the literature, there are just few data about the association between PCT levels and endocarditis and sepsis but there are not etiological differentiations particularly for those sustained by Streptococcus viridans.
|
28387901 |
2017 |
Septicemia
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
The CRP and PCT protein expression results of the sepsis patients were higher than those of the control group.
|
28962140 |
2017 |
Septicemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
In conclusion, 1,25(OH)D but not 25(OH)D showed a minor discriminatory value for the prediction of bacteraemia that was inferior to CRP and PCT but both failed to predict sepsis and mortality in a prospective cohort of SIRS patients.
|
28079172 |
2017 |
Septicemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
The area under ROC curve showed that the clinical accuracy of microRNA-25 for sepsis diagnosis was better than CRP and PCT (AUG=0.806, 0.676 and 0.726, P<0.05).The decrease in level of microRNA-25 was correlated with the severity of sepsis, SOFA score, CRP and PCT level, meanwhile, microRNA-25 level can be used for predicting the prognosis of patients, the patients with microRNA-25 level ≤0.492 had a lower 28 d survival rate.
|
26339334 |
2015 |
Septicemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
The present study is the first to demonstrate the decreased expression of CRISPLD2 in septic shock and its association with PCT in sepsis.
|
23799041 |
2013 |
Septicemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
Our results indicate that the DNA methylation pattern of the promoter region of the CALCA gene varies in different types of bacterial preterm sepsis, thus suggesting a potential use as an epigenetic biomarker.
|
24135723 |
2013 |
Septicemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
To explore the roles of peripheral blood mononuclear cells (PBMCs) and PBMC-derived macrophages in sepsis-related increased procalcitonin and calcitonin gene-related peptide (CGRP) I production.
|
15286549 |
2004 |
Septicemia
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Circulating levels of calcitonin precursors (CTpr), including procalcitonin (ProCT), increase up to several thousand-fold in human sepsis, and immunoneutralization improves survival in two animal models of this disease.
|
12960010 |
2003 |
Septicemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
There is no evidence of plasma PCT binding to cellular receptors of calcitonin, and the role of PCT in calcium and phosphate metabolism during sepsis is still not clear.
|
10984072 |
2000 |
Septicemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
Because of a certain association between increased levels of PCT and leukocyte-derived cytokines during sepsis, we assessed the possible expression of PCT in human peripheral blood mononuclear cells (PBMCs) and the modulation of PCT by lipopolysaccharides (LPS) and various sepsis-related cytokines by reverse transcriptase-polymerase chain reaction (RT-PCR) by using a novel primer set and flow cytometric analysis with intracellular staining with antibodies to the PCT components calcitonin and katacalcin.
|
10402059 |
1999 |