|
Leukemia, Myelocytic, Acute
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.
|
27903959 |
2017 |
|
Hydrops Fetalis, Non-Immune
|
0.100 |
GeneticVariation
|
disease |
CLINVAR |
Identification of embryonic lethal genes in humans by autozygosity mapping and exome sequencing in consanguineous families.
|
26036949 |
2015 |
|
Autistic Disorder
|
0.100 |
GeneticVariation
|
disease |
GWASDB |
Individual common variants exert weak effects on the risk for autism spectrum disorders.
|
22843504 |
2012 |
|
Narcolepsy
|
0.100 |
GeneticVariation
|
disease |
GWASDB |
Genome-wide association database developed in the Japanese Integrated Database Project.
|
19629137 |
2009 |
|
Liver carcinoma
|
0.060 |
GeneticVariation
|
disease |
BEFREE |
A GALNT14 rs9679162 genotype-guided therapeutic strategy for advanced hepatocellular carcinoma: systemic or hepatic arterial infusion chemotherapy.
|
31611591 |
2020 |
|
Malignant neoplasm of breast
|
0.060 |
Biomarker
|
disease |
BEFREE |
We have shown that GALNT14 could promote breast cancer cell invasion.
|
29428518 |
2018 |
|
Malignant neoplasm of breast
|
0.060 |
AlteredExpression
|
disease |
BEFREE |
The expression of GALNT14 is associated with MDR in breast cancer.
|
29702465 |
2018 |
|
Breast Carcinoma
|
0.060 |
Biomarker
|
disease |
BEFREE |
We have shown that GALNT14 could promote breast cancer cell invasion.
|
29428518 |
2018 |
|
Breast Carcinoma
|
0.060 |
AlteredExpression
|
disease |
BEFREE |
The expression of GALNT14 is associated with MDR in breast cancer.
|
29702465 |
2018 |
|
Liver carcinoma
|
0.060 |
GeneticVariation
|
disease |
BEFREE |
Combinations of single nucleotide polymorphisms WWOX-rs13338697, GALNT14-rs9679162 and rs6025211 effectively stratify outcomes of chemotherapy in advanced hepatocellular carcinoma.
|
28695683 |
2018 |
|
Malignant neoplasm of breast
|
0.060 |
AlteredExpression
|
disease |
BEFREE |
Conversely, overexpression of GALNT14 in Osx-knockdown cells abrogated the increased chemosensitivity in breast cancer cells.
|
29227978 |
2017 |
|
Malignant neoplasm of breast
|
0.060 |
Biomarker
|
disease |
BEFREE |
The link among GALNT14, its downstream pathways and lung metastasis, provides us with an opportunity to develop effective therapeutic intervention for breast cancer.[BMB Reports 2017; 50(5): 233-234].
|
28347399 |
2017 |
|
Breast Carcinoma
|
0.060 |
Biomarker
|
disease |
BEFREE |
The link among GALNT14, its downstream pathways and lung metastasis, provides us with an opportunity to develop effective therapeutic intervention for breast cancer.[BMB Reports 2017; 50(5): 233-234].
|
28347399 |
2017 |
|
Breast Carcinoma
|
0.060 |
AlteredExpression
|
disease |
BEFREE |
Conversely, overexpression of GALNT14 in Osx-knockdown cells abrogated the increased chemosensitivity in breast cancer cells.
|
29227978 |
2017 |
|
Malignant neoplasm of breast
|
0.060 |
Biomarker
|
disease |
BEFREE |
Collectively, our findings uncover an unprecedented role for GALNT14 in the pulmonary metastasis of breast cancer and elucidate the underlying molecular mechanisms.
|
27982029 |
2016 |
|
Breast Carcinoma
|
0.060 |
Biomarker
|
disease |
BEFREE |
Collectively, our findings uncover an unprecedented role for GALNT14 in the pulmonary metastasis of breast cancer and elucidate the underlying molecular mechanisms.
|
27982029 |
2016 |
|
Liver carcinoma
|
0.060 |
GeneticVariation
|
disease |
BEFREE |
N-acetylgalactosaminyltransferase 14 (GALNT14)-rs9679162 genotype is a prognostic predictor for chemotherapy response in advanced hepatocellular carcinoma.
|
27124048 |
2016 |
|
Liver carcinoma
|
0.060 |
GeneticVariation
|
disease |
BEFREE |
Transcatheter arterial chemoembolization is currently the standard treatment in hepatocellular carcinoma patients with Barcelona Clinic Liver Cancer stage B. Genomic variants of GALNT14 were recently identified as effective predictors for chemotherapy responses in Barcelona Clinic Liver Cancer stage C patients.
|
26871639 |
2016 |
|
Malignant neoplasm of breast
|
0.060 |
AlteredExpression
|
disease |
BEFREE |
Here, we report that N-acetylgalactosaminyltransferase14 (GALNT14), which mediates the initial step of mucin-type O-glycosylation and is heterogeneously expressed in most breast cancers, plays a critical role in the invasion and migration of breast cancers by regulating the activity of MMP-2 and expression of some EMT genes.
|
24962947 |
2015 |
|
Breast Carcinoma
|
0.060 |
Biomarker
|
disease |
BEFREE |
These findings indicate that GALNT14 contributes to breast cancer invasion by altering the cell proliferation, motility, expression levels of EMT genes, and by stimulating MMP-2 activity, suggesting GALNT14 may be a potential target for breast cancer treatment.
|
24962947 |
2015 |
|
Liver carcinoma
|
0.060 |
GeneticVariation
|
disease |
BEFREE |
A single nucleotide polymorphism on the GALNT14 gene as an effective predictor of response to chemotherapy in advanced hepatocellular carcinoma.
|
23959947 |
2014 |
|
Liver carcinoma
|
0.060 |
GeneticVariation
|
disease |
BEFREE |
The rs9679162 GALNT14 genotype is potentially associated with the objective response of the first course of FMP chemotherapy in patients with far advanced hepatocellular carcinoma.
|
21635146 |
2011 |
|
Tumor Cell Invasion
|
0.040 |
GeneticVariation
|
phenotype |
BEFREE |
Exploratory subgroup analysis showed that <i>GALNT14"TT"</i> genotype was associated with unfavorable OS in SRCCs with more aggressive phenotypes: node status >0 (P = 0.0013), lymphatic invasion (P = 0.021), vascular invasion (P = 0.0076) and perineural invasion (P = 0.0161).
|
30310511 |
2018 |
|
Tumor Cell Invasion
|
0.040 |
AlteredExpression
|
phenotype |
BEFREE |
EFEMP2 significantly increased the invasion ability of breast cancer cells including MCF-7 and MBA-MD-231 cells, and this phenomenon is suppressed by knockdown expression of GALNT14.
|
29428518 |
2018 |
|
Tumor Cell Invasion
|
0.040 |
Biomarker
|
phenotype |
BEFREE |
Knockdown of GALNT14 reduced clonogenicity and attenuates cell migration and cell invasion.
|
24962947 |
2015 |