HRX, Hyperreflexia, 7974

N. diseases: 27; N. variants: 0
Disease: Trisomy 11 ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0432409
Disease: Trisomy 11
Trisomy 11 		0.020 GeneticVariation disease BEFREE We recently discovered that approximately 90% of adult patients with de novo AML and trisomy 11 (+11) as a sole abnormality and 11% of adult patients with de novo AML and normal cytogenetics carry a molecular rearrangement of the ALL1 (MLL, HRX, or HTRX) gene. 9108076 1997
CUI: C0432409
Disease: Trisomy 11
Trisomy 11 		0.020 GeneticVariation disease BEFREE We have characterized two cases of partial HRX duplication in acute leukemias bearing trisomy 11 as the sole chromosomal abnormality. 7658717 1995