Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.030 GeneticVariation disease BEFREE Lipid metabolism plays an important role in Alzheimer's disease (AD), and recent evidence suggests that single nucleotide polymorphisms (SNPs) in the StAR-related lipid transfer domain 6 (<i>STARD6</i>) and near the enzyme enoyl CoA hydratase domain containing 3 (<i>ECHDC3</i>) gene are related to plasma lipid levels or lipid traits in AD. 30666118 2019
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.030 Biomarker disease BEFREE We also associated USP6NL/ECHDC3 and BZRAP1-AS1 to AD, confirming findings from a follow-up transethnic study. 30591712 2018
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.030 AlteredExpression disease BEFREE We also found that gene expression of HS3ST1 and ECHDC3 was altered in AD brains compared with control brains. 25862742 2015
CUI: C0007222
Disease: Cardiovascular Diseases
Cardiovascular Diseases 		0.010 AlteredExpression group BEFREE Increased levels of monounsaturated fatty acids, especially oleic acid, and ECHDC3 upregulation in patients with coronary artery lesion suggests that these are independent factors associated with the initial progression of cardiovascular disease. 27586541 2016
CUI: C0948089
Disease: Acute Coronary Syndrome
Acute Coronary Syndrome 		0.010 AlteredExpression disease BEFREE We previously reported a correlation between ECHDC3 upregulation and the severity of acute coronary syndrome. 27586541 2016