ZNF750, zinc finger protein 750, 79755

N. diseases: 20; N. variants: 2
Disease: Psoriasis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0033860
Disease: Psoriasis
Psoriasis 		0.030 GeneticVariation disease BEFREE We assessed the association of psoriasis and its main clinical phenotypes with common variants of three potential psoriasis susceptibility genes: ZNF750, RPTOR and TRAF31P2. 24005976 2014
CUI: C0033860
Disease: Psoriasis
Psoriasis 		0.030 AlteredExpression disease BEFREE Using a promoter functional assay in stimulated human primary keratinocytes, we showed that four ZNF750 promoter and 5' UTR variants displayed a 35-55% reduction of ZNF750 promoter activity, consistent with the promoter activity reduction seen in a Mendelian psoriasis family with a ZNF750 promoter variant. 22185198 2011
CUI: C0033860
Disease: Psoriasis
Psoriasis 		0.030 GeneticVariation disease BEFREE This report suggests that ZNF750 mutations could contribute to psoriasis susceptibility. 18256691 2008
CUI: C0033860
Disease: Psoriasis
Psoriasis 		0.030 GeneticVariation disease LHGDN This report suggests that ZNF750 mutations could contribute to psoriasis susceptibility. 18256691 2008