Schizophrenia
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The results indicate a potentially weaker effect of FZD3 polymorphisms on schizophrenia than that suggested originally and possibly limited to Chinese populations.
|
27755292 |
2016 |
Schizophrenia
|
0.400 |
Biomarker
|
disease |
PSYGENET |
The present and previous findings indicated that genetic variants of the FZD3 gene may affect susceptibility to schizophrenia in Chinese Han and Va populations.
|
22027177 |
2011 |
Schizophrenia
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The present and previous findings indicated that genetic variants of the FZD3 gene may affect susceptibility to schizophrenia in Chinese Han and Va populations.
|
22027177 |
2011 |
Schizophrenia
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The results suggest that there may be interactive effects for schizophrenia among variants of the genes neuregulin 1 (NRG1, 8p22-p11), G72 (13q34), the regulator of G-protein signaling-4 (RGS4, 1q21-q22) and frizzled 3 (FZD3, 8p21).
|
18584117 |
2008 |
Schizophrenia
|
0.400 |
Biomarker
|
disease |
PSYGENET |
FZD3 is unlikely to play a role in the genetic predisposition towards schizophrenia in the Caucasian population.
|
17982906 |
2007 |
Schizophrenia
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
FZD3 is unlikely to play a role in the genetic predisposition towards schizophrenia in the Caucasian population.
|
17982906 |
2007 |
Schizophrenia
|
0.400 |
Biomarker
|
disease |
BEFREE |
Moreover, the meta-analytic result did not support the association between several commonly investigated markers in FZD3 and schizophrenia.
|
16707163 |
2006 |
Schizophrenia
|
0.400 |
Biomarker
|
disease |
PSYGENET |
Moreover, the meta-analytic result did not support the association between several commonly investigated markers in FZD3 and schizophrenia.
|
16707163 |
2006 |
Schizophrenia
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Association study of the frizzled-3 (FZD3) gene with schizophrenia and mood disorders.
|
15657645 |
2005 |
Schizophrenia
|
0.400 |
Biomarker
|
disease |
PSYGENET |
Association study of the frizzled-3 (FZD3) gene with schizophrenia and mood disorders.
|
15657645 |
2005 |
Schizophrenia
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Lack of a genetic association between the frizzled-3 gene and schizophrenia in a British population.
|
15288446 |
2004 |
Schizophrenia
|
0.400 |
Biomarker
|
disease |
PSYGENET |
These results suggested that the FZD3 gene might be involved in the predisposition to schizophrenia.
|
15274031 |
2004 |
Schizophrenia
|
0.400 |
Biomarker
|
disease |
BEFREE |
Although two prior studies have reported associations using limited numbers of SNPs on FZD3, our intensive study failed to support any major contribution of FZD3 to schizophrenia susceptibility.
|
15364045 |
2004 |
Schizophrenia
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
These results suggested that the FZD3 gene might be involved in the predisposition to schizophrenia.
|
15274031 |
2004 |
Schizophrenia
|
0.400 |
GeneticVariation
|
disease |
LHGDN |
These results suggested that the FZD3 gene might be involved in the predisposition to schizophrenia.
|
15274031 |
2004 |
Schizophrenia
|
0.400 |
GeneticVariation
|
disease |
LHGDN |
We found a significant association between schizophrenia and the FZD3 gene in single nucleotide polymorphisms and haplotype analyses.
|
14642436 |
2003 |
Schizophrenia
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
We found a significant association between schizophrenia and the FZD3 gene in single nucleotide polymorphisms and haplotype analyses.
|
14642436 |
2003 |
Schizophrenia
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The global chi-squared test for haplotype transmission also showed a strong association (chi(2) = 48.84, df = 7, p <.000001).The strong association between the FZD3 locus and schizophrenia suggests that the gene itself may play a role in underlying schizophrenia, although a nearby gene responsible for predisposing to the illness cannot be ruled out.
|
14643098 |
2003 |
Hirschsprung Disease
|
0.320 |
Biomarker
|
disease |
BEFREE |
Two key miRNAs (miR-141-3p and miR-30a-3p), the MAPK signaling pathway and two key genes (FZD3 and DOK6) were implicated in the pathogenesis of HSCR.
|
28965333 |
2017 |
Hirschsprung Disease
|
0.320 |
Biomarker
|
disease |
GENOMICS_ENGLAND |
Deregulation of the planar cell polarity genes CELSR3 and FZD3 in Hirschsprung disease.
|
27619161 |
2016 |
Hirschsprung Disease
|
0.320 |
GeneticVariation
|
disease |
BEFREE |
We observed a significant association between the FZD3 rs17059206 polymorphism and HSCR susceptibility (p<0.001).
|
27619161 |
2016 |
Hydrocephalus
|
0.310 |
GeneticVariation
|
disease |
BEFREE |
Partial restoration of frizzled 3 activities in FZD3 mutant mice results in hydrocephalus.
|
24796881 |
2014 |
Hydrocephalus
|
0.310 |
Biomarker
|
disease |
MGD |
Congenital hydrocephalus in genetically engineered mice.
|
21746835 |
2012 |
Psychotic Disorders
|
0.310 |
Biomarker
|
group |
BEFREE |
The FZD3 gene might not play a role in conferring susceptibility to major psychosis in our sample.
|
15657645 |
2005 |
Nonorganic psychosis
|
0.310 |
Biomarker
|
disease |
BEFREE |
The FZD3 gene might not play a role in conferring susceptibility to major psychosis in our sample.
|
15657645 |
2005 |