TFPI2, tissue factor pathway inhibitor 2, 7980

N. diseases: 161; N. variants: 5
Disease: Malignant neoplasm of breast ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.350 Biomarker disease BEFREE TFPI-2 suppresses breast cancer cell proliferation and invasion through regulation of ERK signaling and interaction with actinin-4 and myosin-9. 30258071 2018
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.350 AlteredExpression disease BEFREE Breast cancer data from GOBO displayed increased levels of TFPI-2 and increased survival in patients with ERα+ tumors. 28088469 2017
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.350 Biomarker disease BEFREE Our results suggest that one of the mechanisms by which TFPI-2 inhibits breast cancer cell invasion could be via the regulation of MMP-2 gene transcription. 29051606 2017
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.350 AlteredExpression disease BEFREE An inverse expression of CD24 and TFPI-2 was observed by immunohistochemical analysis of primary breast cancers (N = 1,174). 21984372 2012
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.350 PosttranslationalModification disease BEFREE Here, we have investigated the mechanism of DNA methylation on the repression of TFPI-2 in breast cancer cell lines. 18053161 2007
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.350 Biomarker disease CTD_human ERE-independent ERalpha target genes differentially expressed in human breast tumors. 16298037 2005