|
Eye Color
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genome-wide association studies identify several new loci associated with pigmentation traits and skin cancer risk in European Americans.
|
23548203 |
2013 |
|
Eye Color
|
0.100 |
GeneticVariation
|
phenotype |
GWASDB |
Genome-wide association studies identify several new loci associated with pigmentation traits and skin cancer risk in European Americans.
|
23548203 |
2013 |
|
Malignant Neoplasms
|
0.080 |
Biomarker
|
group |
BEFREE |
VASH2 also stimulated invasion and chemotherapeutic resistance of PC cells and increased the proportion of cancer stem-like cells in PC cells.
|
30318866 |
2018 |
|
Primary malignant neoplasm
|
0.080 |
Biomarker
|
group |
BEFREE |
VASH2 also stimulated invasion and chemotherapeutic resistance of PC cells and increased the proportion of cancer stem-like cells in PC cells.
|
30318866 |
2018 |
|
Malignant Neoplasms
|
0.080 |
AlteredExpression
|
group |
BEFREE |
Vasohibin-2 is mainly expressed in cancer cells, and has been implicated in the progression of cancer by inducing angiogenesis and tumor growth.
|
28064471 |
2017 |
|
Malignant Neoplasms
|
0.080 |
Biomarker
|
group |
BEFREE |
Vasohibin 2 (VASH2) has previously been identified as an agiogenenic factor and a cancer related protein.
|
28327155 |
2017 |
|
Malignant Neoplasms
|
0.080 |
Biomarker
|
group |
BEFREE |
Vasohibins (VASH1 and VASH2) are recently identified regulators of angiogenesis and cancer cell functions.
|
27879017 |
2017 |
|
Primary malignant neoplasm
|
0.080 |
Biomarker
|
group |
BEFREE |
Vasohibins (VASH1 and VASH2) are recently identified regulators of angiogenesis and cancer cell functions.
|
27879017 |
2017 |
|
Primary malignant neoplasm
|
0.080 |
Biomarker
|
group |
BEFREE |
Vasohibin 2 (VASH2) has previously been identified as an agiogenenic factor and a cancer related protein.
|
28327155 |
2017 |
|
Primary malignant neoplasm
|
0.080 |
AlteredExpression
|
group |
BEFREE |
Vasohibin-2 is mainly expressed in cancer cells, and has been implicated in the progression of cancer by inducing angiogenesis and tumor growth.
|
28064471 |
2017 |
|
Malignant Neoplasms
|
0.080 |
Biomarker
|
group |
BEFREE |
Cytoplasmic VASH2 is associated with carcinoma angiogenesis and malignant transformation and promotes cancer growth.
|
26177649 |
2015 |
|
Primary malignant neoplasm
|
0.080 |
Biomarker
|
group |
BEFREE |
Cytoplasmic VASH2 is associated with carcinoma angiogenesis and malignant transformation and promotes cancer growth.
|
26177649 |
2015 |
|
Malignant Neoplasms
|
0.080 |
Biomarker
|
group |
BEFREE |
Vasohibin‑2 (VASH2) is an angiogenic factor, and has been previously reported to be a cancer‑related gene, with cytoplasmic and karyotypic forms.
|
24920244 |
2014 |
|
Primary malignant neoplasm
|
0.080 |
Biomarker
|
group |
BEFREE |
Vasohibin‑2 (VASH2) is an angiogenic factor, and has been previously reported to be a cancer‑related gene, with cytoplasmic and karyotypic forms.
|
24920244 |
2014 |
|
Malignant Neoplasms
|
0.080 |
AlteredExpression
|
group |
BEFREE |
Under hypoxia, both vasohibin-1 and vasohibin-2 expressions were significantly decreased in the distant metastasis cancer cell line Hs-746T, cultured with or without TAMs (P<0.001).
|
22438034 |
2012 |
|
Malignant Neoplasms
|
0.080 |
Biomarker
|
group |
BEFREE |
The knockdown of VASH2 showed little effect on the proliferation of cancer cells in vitro but notably inhibited tumor growth, peritoneal dissemination, and tumor angiogenesis in a murine xenograft model.
|
22826464 |
2012 |
|
Primary malignant neoplasm
|
0.080 |
Biomarker
|
group |
BEFREE |
The knockdown of VASH2 showed little effect on the proliferation of cancer cells in vitro but notably inhibited tumor growth, peritoneal dissemination, and tumor angiogenesis in a murine xenograft model.
|
22826464 |
2012 |
|
Primary malignant neoplasm
|
0.080 |
AlteredExpression
|
group |
BEFREE |
Under hypoxia, both vasohibin-1 and vasohibin-2 expressions were significantly decreased in the distant metastasis cancer cell line Hs-746T, cultured with or without TAMs (P<0.001).
|
22438034 |
2012 |
|
Neoplasms
|
0.070 |
Biomarker
|
group |
BEFREE |
These findings suggest that VASH2 plays an essential role in the metastasis of PDAC with multiple effects on both cancer cells and the tumor microenvironment, including tubulin detyrosination, tumor angiogenesis and evasion of tumor immunity.
|
31074083 |
2019 |
|
Neoplasms
|
0.070 |
AlteredExpression
|
group |
BEFREE |
VASH1 is expressed mainly in endothelial cells to inhibit angiogenesis, whereas VASH2 is expressed mainly in cancer cells to stimulate tumor growth.
|
28032401 |
2017 |
|
Neoplasms
|
0.070 |
Biomarker
|
group |
BEFREE |
As a well‑known angiogenic factor in different histology and pathological conditions, the pro‑progressive role of vasohibin2 (VASH2) has been reported in various types of tumors.
|
29039601 |
2017 |
|
Neoplasms
|
0.070 |
AlteredExpression
|
group |
BEFREE |
Vasohibin-2 is mainly expressed in cancer cells, and has been implicated in the progression of cancer by inducing angiogenesis and tumor growth.
|
28064471 |
2017 |
|
Neoplasms
|
0.070 |
Biomarker
|
group |
BEFREE |
The effect of VASH2 on cell proliferation was investigated using a bromodeoxyuridine assay in vitro and immunohistochemistry of Ki67 in xenograft tumors.
|
24920244 |
2014 |
|
Neoplasms
|
0.070 |
Biomarker
|
group |
BEFREE |
In addition, the siVASH2-treated tumor contained more blood vessels covered with pericytes, indicating that knockdown of VASH2 contributes to the normalization of tumor blood vessels.
|
24118388 |
2013 |
|
Neoplasms
|
0.070 |
Biomarker
|
group |
BEFREE |
When either EL-4 or MLTC-1 cells were inoculated into VASH2 (-/-) mice, the VASH2 transfectants formed bigger tumors when compared with the controls, and the tumor microvessel density was significantly increased.
|
22826464 |
2012 |