DCAF17, DDB1 and CUL4 associated factor 17, 80067

N. diseases: 59; N. variants: 12
Disease: Male infertility ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0021364
Disease: Male infertility
Male infertility 		0.030 GeneticVariation phenotype BEFREE Publisher Correction: Deletion of DDB1- and CUL4- associated factor-17 (Dcaf17) gene causes spermatogenesis defects and male infertility in mice. 30068992 2018
CUI: C0021364
Disease: Male infertility
Male infertility 		0.030 GeneticVariation phenotype BEFREE Although Dcaf17 disruption did not have any effect on female fertility, Dcaf17 deletion led to male infertility due to abnormal sperm development. 29907856 2018
CUI: C0021364
Disease: Male infertility
Male infertility 		0.030 Biomarker phenotype BEFREE A mouse model mimicking loss of function in exon 2 of Dcaf17 was generated using CRISPR/Cas9 and showed female subfertility and male infertility. 29178422 2018