Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0025517
Disease: Metabolic Diseases
Metabolic Diseases
0.020 Biomarker group BEFREE Here, we further investigate the effects of MGAT2 inhibition on 1) fat-induced gut peptide release and fat intake in normal mice and 2) metabolic disorders in high-fat diet (HFD)-fed ob/ob mice, a model of severe obesity and type 2 diabetes mellitus, using an orally bioavailable MGAT2 inhibitor Compound B (CpdB). 31837122 2020
CUI: C0025517
Disease: Metabolic Diseases
Metabolic Diseases
0.020 Biomarker group BEFREE Indeed, mice lacking the enzyme (Mogat2(-/-)) are resistant to obesity and other metabolic disorders induced by high-fat feeding. 21734185 2011