STAM, signal transducing adaptor molecule, 8027

N. diseases: 20; N. variants: 2
Disease: Hyperglycemia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0020456
Disease: Hyperglycemia
Hyperglycemia 		0.020 Biomarker disease BEFREE Similar sex-independent HCC occurred in the "STAM" model of mice, in which severe hyperglycemia and HF feeding results in rapid hepatic lipid deposition, fibrosis, and ultimately HCC. 31575546 2019
CUI: C0020456
Disease: Hyperglycemia
Hyperglycemia 		0.020 Biomarker disease BEFREE These results suggested that the increase in oxidative stress with hyperglycemia triggered hepatic lesions in STAM mice, and insulin resistance promoted lesion formation with hepatic lipid accumulation. 28730823 2017