CUBN, cubilin, 8029

N. diseases: 65; N. variants: 15
Disease: Diabetic Nephropathy ×
Source: BEFREE ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy 		0.220 Biomarker disease BEFREE This study highlights that MMP-9 or CUBN-SNPs may exert effects on risk of susceptibility to DN or ESRD. 30557881 2019
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy 		0.220 Biomarker disease BEFREE We hypothesize that perturbed insulin-Akt cascade in DM leads to alterations in trafficking of megalin and cubilin, which results in urinary cubilin shedding as a prelude to MA in early diabetic nephropathy. 26465605 2015