CUBN, cubilin, 8029

N. diseases: 65; N. variants: 15
Disease: Neural Tube Defects ×
Source: BEFREE ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027794
Disease: Neural Tube Defects
Neural Tube Defects 		0.020 Biomarker group BEFREE We also discuss the role of Cubilin as a modulator of Fgf8 signaling during embryonic development and propose that the Cubilin-Fgf8 interaction may be relevant in human pathology, including in cancer progression, heart or neural tube defects. 30295181 2018
CUI: C0027794
Disease: Neural Tube Defects
Neural Tube Defects 		0.020 Biomarker group BEFREE In rodents, administration of antibodies to cubilin, a component of the intestinal receptor responsible for cobalamin absorption, results in a variety of defects including neural tube defects. 19586788 2009