NCOA4, nuclear receptor coactivator 4, 8031

N. diseases: 62; N. variants: 8
Disease: Iron Overload ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0282193
Disease: Iron Overload
Iron Overload 		0.020 Biomarker disease BEFREE In the present study, we aim to investigate the role of NCOA4-mediated ferritinophagy and SFXN1-dependent mitochondria iron overload in apelin-13-induced cardiomyocytes hypertrophy. 30731113 2019
CUI: C0282193
Disease: Iron Overload
Iron Overload 		0.020 Biomarker disease BEFREE Iron overload in urothelial cells induces ferritinophagy in an NCOA4-dependent manner causing increased iron availability for UPEC, triggering bacterial overproliferation and host cell death. 27002654 2016