LPAL2, lipoprotein(a) like 2, pseudogene, 80350

N. diseases: 53; N. variants: 12
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.160 Biomarker disease BEFREE HDL subpopulations containing apoA-I without apoA-II (LpA-I) in patients with angiographically proven coronary artery disease. 27169356 2017
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.160 GeneticVariation disease BEFREE Functional Variant in the SLC22A3-LPAL2-LPA Gene Cluster Contributes to the Severity of Coronary Artery Disease. 27417586 2016
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.160 GeneticVariation disease BEFREE Relatively low numbers of kringle 4 type 2 repeats in apolipoprotein(a) and specific haplotypes of the SLC22A3-LPAL2-LPA region on chromosome 6 are associated with an increased risk of coronary disease. 23278389 2013
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.160 GeneticVariation disease BEFREE Lack of association between four SNPs in the SLC22A3-LPAL2-LPA gene cluster and coronary artery disease in a Chinese Han population: a case control study. 23036009 2012
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.160 GeneticVariation disease GWASCAT Genome-wide haplotype association study identifies the SLC22A3-LPAL2-LPA gene cluster as a risk locus for coronary artery disease. 19198611 2009
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.160 GeneticVariation disease BEFREE Genome-wide haplotype association study identifies the SLC22A3-LPAL2-LPA gene cluster as a risk locus for coronary artery disease. 19198611 2009
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.160 Biomarker disease BEFREE Children of parents with CHD differed from controls in total cholesterol and apolipoprotein A II concentrations. 1929512 1991
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.150 GeneticVariation disease GWASCAT Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease. 29212778 2018
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.150 Biomarker disease BEFREE HDL subpopulations containing apoA-I without apoA-II (LpA-I) in patients with angiographically proven coronary artery disease. 27169356 2017
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.150 GeneticVariation disease BEFREE One single nucleotide polymorphism, rs3088442, in the SLC22A3-LPAL2-LPA gene cluster was significantly associated with both plasma Lp(a) levels and CAD severity. 27417586 2016
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.150 GeneticVariation disease BEFREE Relatively low numbers of kringle 4 type 2 repeats in apolipoprotein(a) and specific haplotypes of the SLC22A3-LPAL2-LPA region on chromosome 6 are associated with an increased risk of coronary disease. 23278389 2013
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.150 GeneticVariation disease BEFREE We for the first time explored the association of the four SNPs in the SLC22A3-LPAL2-LPA gene cluster with CAD in a large Chinese Han sample. 23036009 2012
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.150 GeneticVariation disease BEFREE Genome-wide haplotype association study identifies the SLC22A3-LPAL2-LPA gene cluster as a risk locus for coronary artery disease. 19198611 2009
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.150 GeneticVariation disease GWASDB Genome-wide haplotype association study identifies the SLC22A3-LPAL2-LPA gene cluster as a risk locus for coronary artery disease. 19198611 2009
CUI: C0003850
Disease: Arteriosclerosis
Arteriosclerosis
0.100 Biomarker disease BEFREE The important role of apolipoprotein A-II in ezetimibe driven reduction of high cholesterol diet-induced atherosclerosis. 30500605 2019
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis
0.100 Biomarker disease BEFREE The important role of apolipoprotein A-II in ezetimibe driven reduction of high cholesterol diet-induced atherosclerosis. 30500605 2019
CUI: C1096202
Disease: Lipoprotein (a) measurement
Lipoprotein (a) measurement
0.100 GeneticVariation phenotype GWASCAT A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms. 28512139 2017
CUI: C1096202
Disease: Lipoprotein (a) measurement
Lipoprotein (a) measurement
0.100 GeneticVariation phenotype GWASCAT Genome- and exome-wide association study of serum lipoprotein (a) in the Jackson Heart Study. 26377243 2015
CUI: C0003850
Disease: Arteriosclerosis
Arteriosclerosis
0.100 Biomarker disease BEFREE Human apolipoprotein A-II protects against diet-induced atherosclerosis in transgenic rabbits. 23241412 2013
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis
0.100 Biomarker disease BEFREE Human apolipoprotein A-II protects against diet-induced atherosclerosis in transgenic rabbits. 23241412 2013
CUI: C0202236
Disease: Triglycerides measurement
Triglycerides measurement
0.100 GeneticVariation phenotype GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622 2012
CUI: C0003850
Disease: Arteriosclerosis
Arteriosclerosis
0.100 Biomarker disease BEFREE Apolipoprotein A-II (APOA2) plays an ambiguous role in lipid metabolism, obesity, and atherosclerosis. 17446329 2007
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis
0.100 Biomarker disease BEFREE Apolipoprotein A-II (APOA2) plays an ambiguous role in lipid metabolism, obesity, and atherosclerosis. 17446329 2007
CUI: C0003850
Disease: Arteriosclerosis
Arteriosclerosis
0.100 Biomarker disease BEFREE Apolipoprotein A-II, HDL metabolism and atherosclerosis. 12119188 2002
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis
0.100 Biomarker disease BEFREE Apolipoprotein A-II, HDL metabolism and atherosclerosis. 12119188 2002