TNKS2, tankyrase 2, 80351

N. diseases: 25; N. variants: 4
Disease: Adenocarcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma 		0.010 GeneticVariation group BEFREE However, patients carrying TNKS2 rs1340420 G/G and A/G genotypes were associated with a lower risk of developing NSCLC and adenocarcinoma (OR=0.14; 95% CI=0.02-1.15 and OR=0.11; 95% CI=0.03-0.91, respectively), whereas females patients homozygous for the TNKS2 rs1770474 T allele, a rare type, were associated with a higher risk of developing squamous-cell carcinoma (SCC) (OR=4.67; 95% CI=0.87-25.01). 26293798 2015