ADAM12, ADAM metallopeptidase domain 12, 8038

N. diseases: 107; N. variants: 19
Disease: Benign Neoplasm ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0086692
Disease: Benign Neoplasm
Benign Neoplasm 		0.020 AlteredExpression group BEFREE For non-LCM samples, it was obtained also an increased expression for ADAM12 and 17 genes in cancers, while in benign tumors only ADAM12 variants were significantly up-regulated compared to controls. 21240579 2011
CUI: C0086692
Disease: Benign Neoplasm
Benign Neoplasm 		0.020 AlteredExpression group BEFREE In vivo, the steady-state of both ADAM9 and ADAM12 mRNA levels was nearly undetectable in both normal livers and benign tumors and increased in hepatocellular carcinomas (up to 3- and 6-fold, respectively) and liver metastases from colonic carcinomas (up to 40- and 60-fold, respectively). 12717386 2003