FGF23, fibroblast growth factor 23, 8074

N. diseases: 305; N. variants: 19
Disease: Renal Insufficiency ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1565489
Disease: Renal Insufficiency
Renal Insufficiency 		0.070 Biomarker disease BEFREE Early renal dysfunction and fibroblast growth factor-23 in patients with small vessel disease-related stroke. 31659218 2019
CUI: C1565489
Disease: Renal Insufficiency
Renal Insufficiency 		0.070 AlteredExpression disease BEFREE Thus, the presence of high circulating FGF23 levels alone in the absence of renal impairment and normal/high phosphate levels is not sufficient to cause cardiovascular disease. 29735309 2018
CUI: C1565489
Disease: Renal Insufficiency
Renal Insufficiency 		0.070 AlteredExpression disease BEFREE FGF23 plasma levels increase in the early stage of renal insufficiency to prevent hyperphosphatemia. 29618028 2018
CUI: C1565489
Disease: Renal Insufficiency
Renal Insufficiency 		0.070 AlteredExpression disease BEFREE 10-week-old 129Sv-Col4a3KO mice showed impaired renal function (blood urea nitrogen 191 ± 39 versus 34 ± 4 mg/dL), hyperphosphatemia (14.1 ± 1.4 versus 6.8 ± 0.3 mg/dL) and 33-fold higher serum FGF23 levels (P < 0.05 versus WT for each). 29309658 2018
CUI: C1565489
Disease: Renal Insufficiency
Renal Insufficiency 		0.070 AlteredExpression disease BEFREE Fibroblast growth factor 23 (FGF-23) levels are elevated in impaired renal function. 28721153 2017
CUI: C1565489
Disease: Renal Insufficiency
Renal Insufficiency 		0.070 Biomarker disease BEFREE The findings suggest that the Klotho-FGF23-FGFR system is active in coronary arteries and its upregulation correlates with impaired renal function and matrix calcium deposition. 24459137 2014
CUI: C1565489
Disease: Renal Insufficiency
Renal Insufficiency 		0.070 Biomarker disease LHGDN Possible involvement of circulating fibroblast growth factor 23 in the development of secondary hyperparathyroidism associated with renal insufficiency. 15264182 2004