ACTN4, actinin alpha 4, 81

N. diseases: 166; N. variants: 10
Disease: Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007097
Disease: Carcinoma
Carcinoma 		0.320 AlteredExpression group BEFREE BACKGROUND alpha-actinin-4 (Actinin-4 or ACTN4), originally identified as an actin-binding protein associated with the biological function of cancer cells, appears to be highly expressed in numerous human epithelial carcinomas, including breast cancer (BC). 31054253 2019
CUI: C0007097
Disease: Carcinoma
Carcinoma 		0.320 Biomarker group BEFREE Copy number increase (CNI) of ACTN4 has been associated with poor prognosis and metastatic phenotypes in various human carcinomas. 24574362 2014
CUI: C0007097
Disease: Carcinoma
Carcinoma 		0.320 Biomarker group CTD_human cDNA microarray profiling of rat mammary gland carcinomas induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and 7,12-dimethylbenz[a]anthracene. 12376462 2002