|
Cleft palate with cleft lip
|
0.100 |
Biomarker
|
disease |
BEFREE |
We have identified Cleft Lip and Palate Transmembrane 1-Like (CLPTM1L)/Cisplatin Resistance Related Protein 9 (CRR9) as an ER stress related mediator of cytoprotection in pancreatic cancer.
|
30468251 |
2019 |
|
Cleft palate with cleft lip
|
0.100 |
Biomarker
|
disease |
BEFREE |
Variants of the cleft lip and palate trans-membrane 1 like (CLPTM1L) gene, located on chromosome 5p15.33, were previously determined to influence lung cancer susceptibility.
|
26852039 |
2016 |
|
Cleft palate with cleft lip
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Several recent studies have provided evidence that rs401681 polymorphisms in intronic region of cleft lip and palate trans-membrane 1-like (CLPTM1L) gene sequence are associated with pancreatic cancer (PC) development, but a comprehensive synopsis is not available.
|
25284078 |
2015 |
|
Cleft palate with cleft lip
|
0.100 |
Biomarker
|
disease |
BEFREE |
Using bioinformatics analyses, we found that cleft lip and palate transmembrane 1-like (CLPTM1L) was a potential target of miR-494.
|
25480402 |
2015 |
|
Cleft palate with cleft lip
|
0.100 |
Biomarker
|
disease |
BEFREE |
Genome-wide association studies in several ethnic groups have reported that polymorphisms of the telomerase reverse transcriptase (TERT) and cleft lip and palate transmembrane 1-like (CLPTM1L) genes, located on 5p15.33, are associated with susceptibility to lung cancer.
|
25966219 |
2015 |
|
Cleft palate with cleft lip
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Genetic variants of cleft lip and palate trans-membrane 1-like (CLPTM1L) genes in the p15.33 region of chromosome 5 were previously identified to influence susceptibility to lung cancer.
|
25526467 |
2014 |
|
Cleft palate with cleft lip
|
0.100 |
Biomarker
|
disease |
BEFREE |
The Cleft lip and palate transmembrane 1-like (CLPTM1L) gene resides in a locus in the chromosome 5p15.33 region that is associated with lung cancer susceptibility and has a role in carcinogenesis.
|
25155038 |
2014 |
|
Cleft palate with cleft lip
|
0.100 |
Biomarker
|
disease |
BEFREE |
Recently, some genome-wide association studies have implicated telomerase reverse transcriptase (TERT) and cleft lip and palate transmembrane 1-like gene (CLPTM1L) in lung cancer development.
|
24861918 |
2014 |
|
Cleft palate with cleft lip
|
0.100 |
Biomarker
|
disease |
BEFREE |
Telomerase reverse transcriptase (TERT) and cleft lip and palate trans-membrane 1 like (CLPTM1L) genes located on chromosome 5p15.33 are known to influence the susceptibility to various cancers.
|
25339005 |
2014 |
|
Cleft palate with cleft lip
|
0.100 |
Biomarker
|
disease |
BEFREE |
Genetic polymorphisms of telomerase reverse transcriptase (TERT) and cleft lip and palate transmembrane 1-like (CLPTM1L) genes in chromosome 5p15.33 region were previously identified to influence the risks of lung cancer.
|
25037574 |
2014 |
|
Cleft palate with cleft lip
|
0.100 |
Biomarker
|
disease |
BEFREE |
This study was conducted to investigate the association between single nucleotide polymorphisms (SNPs) in telomerase reverse transcriptase (TERT) and cleft lip and palate transmembrane1-like (CLPTM1L) and lung cancer risk in a Chinese population.
|
24761905 |
2014 |
|
Cleft palate with cleft lip
|
0.100 |
Biomarker
|
disease |
BEFREE |
Rs31489 in the cleft lip and palate transmembrane1-like gene (CLPTM1L) has been identified to be associated with lung cancer through genome-wide association studies (GWAS).
|
25422207 |
2014 |
|
Cleft palate with cleft lip
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Common genetic polymorphisms on chromosome 5p15.33, including rs401681 in cleft lip and palate transmembrane 1-like gene (CLPTM1L), have been implicated in susceptibility to lung cancer through genome-wide association studies (GWAS); however, subsequent replication studies yielded controversial results.
|
23653681 |
2013 |
|
Cleft palate with cleft lip
|
0.100 |
Biomarker
|
disease |
BEFREE |
This is the first report of a possible connection between CLPTM1L and CLP.
|
23395979 |
2013 |
|
Cleft palate with cleft lip
|
0.100 |
Biomarker
|
disease |
BEFREE |
Genetic variants of telomerase reverse transcriptase (TERT) and cleft lip and palate trans-membrane 1 like (CLPTM1L) genes in chromosome 5p15.33 region were previously identified to influence the susceptibility to lung cancer.
|
23433592 |
2013 |
|
Cleft palate with cleft lip
|
0.100 |
Biomarker
|
disease |
BEFREE |
The human 5p15.33 locus contains two well-known genes, the telomerase reverse transcriptase (TERT) and cleft lip and palate transmembrane 1-like (CLPTM1L) genes, which have been implicated in carcinogenesis.
|
24386361 |
2013 |
|
Cleft palate with cleft lip
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Because the TERT locus includes the cleft lip and palate transmembrane 1-like (CLPTM1L) gene, which is in linkage disequilibrium with TERT, CLPTM1L polymorphisms were also analyzed.
|
22523397 |
2012 |
|
Cleft palate with cleft lip
|
0.100 |
Biomarker
|
disease |
BEFREE |
A few single-nucleotide polymorphisms (SNPs) in the telomerase reverse transcriptase (TERT) and cleft lip and palate transmembrane 1-like (CLPTM1L) genes located in this region have shown consistent associations.
|
21771723 |
2011 |