CALR, calreticulin, 811

N. diseases: 487; N. variants: 9
Disease: Acute monocytic leukemia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0023465
Disease: Acute monocytic leukemia
Acute monocytic leukemia 		0.040 GeneticVariation disease BEFREE AML transformation occurred faster in SMF than in PMF and patients who transformed to AML were more SRSF2-mutated and less CALR-mutated at MF sampling. 31340059 2019
CUI: C0023465
Disease: Acute monocytic leukemia
Acute monocytic leukemia 		0.040 Biomarker disease BEFREE Calreticulin exposure by malignant blasts correlates with robust anticancer immunity and improved clinical outcome in AML patients. 27802968 2016
CUI: C0023465
Disease: Acute monocytic leukemia
Acute monocytic leukemia 		0.040 Biomarker disease BEFREE The angiogenesis inhibitor vasostatin is regulated by neutrophil elastase-dependent cleavage of calreticulin in AML patients. 22915645 2012
CUI: C0023465
Disease: Acute monocytic leukemia
Acute monocytic leukemia 		0.040 AlteredExpression disease BEFREE CBFB-SMMHC is correlated with increased calreticulin expression and suppresses the granulocytic differentiation factor CEBPA in AML with inv(16). 15855281 2005