|
Hyperplastic Polyp
|
0.100 |
Biomarker
|
disease |
BEFREE |
Neither a mucus cap nor CP-II meshed capillary vessels showed statistical significance in differentiating SSA/P from HP (P = 0.590 and 0.293, respectively).
|
30693669 |
2019 |
|
Hyperplastic Polyp
|
0.100 |
Biomarker
|
disease |
BEFREE |
Because HP versus SSP is not very reproducible the predictors of SSA/P that we identified, including size, location, and synchronous lesions, can offer some additional help to endoscopists when determining surveillance intervals in patients with serrated polyps.
|
28723863 |
2018 |
|
Hyperplastic Polyp
|
0.100 |
Biomarker
|
disease |
BEFREE |
These associations applied similarly to HP (1.47, 1.44-1.50), TA (1.30, 1.27-1.32), and SSA/P (1.52, 1.46-1.58).
|
29147879 |
2018 |
|
Hyperplastic Polyp
|
0.100 |
Biomarker
|
disease |
BEFREE |
For large serrated polyp, NBI in combination with CE had a better accuracy than NBI alone (91% vs 86%, P = 0.025) to distinguish SSA/P from HP.
|
28687028 |
2018 |
|
Hyperplastic Polyp
|
0.100 |
Biomarker
|
disease |
BEFREE |
Compared with the lesions without cancer, the lesions with cancer exhibited a larger size (HP, TSA and SSA/P), a reddish appearance (SSA/P), a two-tier raised appearance (HP and SSA/P), a central depression (HP, TSA and SSA/P), the type V pit pattern (HP, TSA and SSA/P), and/or the type III capillary pattern (TSA and SSA/P).
|
29805602 |
2018 |
|
Hyperplastic Polyp
|
0.100 |
Biomarker
|
disease |
BEFREE |
By using colonoscopies in adults aged ≥50 years (4/09-12/14), we stratified endoscopists by high and low ADRs (<15%, 15%-<25%, 25%-<35%, ≥35%) to determine corresponding SDRs by using 2 SDR measures, for screening and surveillance colonoscopies separately: (1) Clinically significant SDR (CSSDR), meaning colonoscopies with any sessile serrated adenoma/polyp (SSA/P), traditional serrated adenoma (TSA), or hyperplastic polyp (HP) >1 cm anywhere in the colon or HP >5 mm in the proximal colon only divided by the total number of screening and surveillance colonoscopies, respectively.
|
28153571 |
2017 |
|
Hyperplastic Polyp
|
0.100 |
Biomarker
|
disease |
BEFREE |
We performed immunohistochemistry for Ki67, p16INK4a, and WNT5A in human HPs (n=22), SSA/Ps (n=41), and TSAs (n=19).
|
28627675 |
2017 |
|
Hyperplastic Polyp
|
0.100 |
Biomarker
|
disease |
BEFREE |
To determine whether an educational intervention that improved adenoma detection rate (ADR) could improve SSA/P detection rate after reclassification of previously termed "hyperplastic" polyps.
|
28444509 |
2017 |
|
Hyperplastic Polyp
|
0.100 |
Biomarker
|
disease |
BEFREE |
Overall, the mucin and associated O-glycan based panel defined in the present study could aid in discriminating SSA/P from HP to devise better colon surveillance strategies.
|
27705923 |
2017 |
|
Hyperplastic Polyp
|
0.100 |
Biomarker
|
disease |
BEFREE |
Furthermore, the possibility has been raised that pathologists misclassify SSA/P as hyperplastic polyp.
|
27376251 |
2017 |
|
Hyperplastic Polyp
|
0.100 |
Biomarker
|
disease |
BEFREE |
The pattern of microRNAs in screen-detected polyps in relation to histologic features and cancer risk has not been investigated. miRNA expression analysis was performed on normal mucosa (NM), hyperplastic polyps (HP), tubular adenomas (TA), tubulovillous adenomas or high-grade dysplasia (TVHG), and serrated polyps [sessile serrated adenoma/polyps (SSA/P) and traditional serrated adenomas (TSA)] in biopsy specimens from 109 patients undergoing screening/surveillance colonoscopy.
|
27658891 |
2016 |
|
Hyperplastic Polyp
|
0.100 |
Biomarker
|
disease |
BEFREE |
Because HPs and SSA/Ps cover the morphological spectrum, we hypothesized that an intermediate serrated polyp (ISP) might exist between an HP and an SSA/P in terms of both morphological and molecular aspects.
|
24935059 |
2014 |
|
Hyperplastic Polyp
|
0.100 |
Biomarker
|
disease |
BEFREE |
A significant proportion of HP or SSA/P precursor lesions accompanied by TSAs can be detected by endoscopy based on both their flat-elevated growth and type II pit patterns.
|
24225759 |
2013 |
|
Hyperplastic Polyp
|
0.100 |
Biomarker
|
disease |
BEFREE |
Serrated (hyperplastic) polyposis (SP) is a rare disorder with multiple colorectal hyperplastic polyps and often sessile serrated adenomas/polyps (SSA/P) or adenomas.
|
22490521 |
2013 |
|
Hyperplastic Polyp
|
0.100 |
Biomarker
|
disease |
BEFREE |
BRAF mutation was mainly detected in SSA/P with dysplasia (95%), SSA/P (85%), microvesicular HP (76%), and traditional serrated adenoma (54%), whereas KRAS mutation was present mainly in goblet cell HP (50%) and in tubulovillous adenoma (45%).
|
22510757 |
2012 |
|
Hyperplastic Polyp
|
0.100 |
Biomarker
|
disease |
BEFREE |
A proximal site characterised SSA/P/L compared with BBSA/P/L and HP (p<0.0001).
|
22782936 |
2012 |
|
Hyperplastic Polyp
|
0.100 |
Biomarker
|
disease |
BEFREE |
Hyperplastic polyps (HPs) share some histologic and molecular characteristics with SSA/P, but it is unclear whether SSA/Ps are derived from HPs or whether they develop by a different pathogenetic pathway.
|
21836485 |
2011 |