SLC7A5, solute carrier family 7 member 5, 8140

N. diseases: 173; N. variants: 3
Disease: Childhood Glioblastoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0280474
Disease: Childhood Glioblastoma
Childhood Glioblastoma 		0.040 Biomarker disease BEFREE New fluoroethyl phenylalanine analogues as potential LAT1-targeting PET tracers for glioblastoma. 30814660 2019
CUI: C0280474
Disease: Childhood Glioblastoma
Childhood Glioblastoma 		0.040 Biomarker disease BEFREE 2-[<sup>18</sup>F]FELP, a novel LAT1-specific PET tracer, for the discrimination between glioblastoma, radiation necrosis and inflammation. 31841816 2019
CUI: C0280474
Disease: Childhood Glioblastoma
Childhood Glioblastoma 		0.040 Biomarker disease BEFREE Xenopus laevis oocytes expressing human LAT1 together with the glycoprotein 4F2hc (necessary to pull LAT-1 to the plasma membrane) exhibited a similar accumulation of FET as observed in glioblastoma cells. 25385314 2015
CUI: C0280474
Disease: Childhood Glioblastoma
Childhood Glioblastoma 		0.040 Biomarker disease BEFREE We have focused our attention on the PDZ domain from hCASK (Human calcium/calmodulin-dependent serine protein kinase) that binds extracellular CD98 in epithelial cells, being this antigen recognized as a marker for several human tumors and particularly considered a negative prognostic marker for human glioblastoma. 25581839 2015