CFHR5, complement factor H related 5, 81494

N. diseases: 43; N. variants: 14
Disease: IGA Glomerulonephritis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0017661
Disease: IGA Glomerulonephritis
IGA Glomerulonephritis 		0.030 AlteredExpression disease BEFREE Circulating FHR-5 levels were significantly elevated in patients with IgAN compared to healthy individuals (median 4.55 [interquartile range 3.58 to 5.85] μg/ml vs 3.19 [interquartile range 2.55 to 3.92] μg/ml). 29759419 2018
CUI: C0017661
Disease: IGA Glomerulonephritis
IGA Glomerulonephritis 		0.030 Biomarker disease BEFREE Serum FHR5 was slightly elevated in IgAN but did not correlate with eGFR. 28673452 2017
CUI: C0017661
Disease: IGA Glomerulonephritis
IGA Glomerulonephritis 		0.030 Biomarker disease BEFREE Our study found that rare variants in CFHR5 may contribute to the genetic susceptibility to IgAN, which suggests that CFHR5 is an IgAN susceptibility gene. 26825529 2016