Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2718017
Disease: TDP-43 Proteinopathies
TDP-43 Proteinopathies
0.010 AlteredExpression disease BEFREE Our results demonstrate that Camk2a-directed 208 TDP-43 CTF overexpression is sufficient to cause hippocampal pathology and neurodegeneration in vivo, suggesting an active role for TDP-43 CTFs in the pathogenesis of FTLD-TDP and related TDP-43 proteinopathies. 26476406 2015