Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Red cell distribution width determination
0.100 GeneticVariation phenotype GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
RDW - Red blood cell distribution width result
0.100 GeneticVariation phenotype GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
CUI: C0856825
Disease: Acute GVH disease
Acute GVH disease
0.020 Biomarker disease BEFREE Recent data have suggested that a pleiotropic T-cell immunomodulatory protein (TIP) could effectively mediate inflammatory cytokines of mammalian immune response against acute graft-versus-host disease in animal models. 31104402 2019
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.020 Biomarker phenotype BEFREE ExPEC harboring a deletion of the gene encoding the mannose-binding type 1 pilus tip protein FimH demonstrated reduced binding and invasion compared to strains lacking known <i>E. coli</i> virulence factors. 28808163 2017
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.020 Biomarker phenotype BEFREE The interaction between RUVBL1 and ITFG1 is required for breast cancer cell collective invasion and progression. 28341484 2017
CUI: C0856825
Disease: Acute GVH disease
Acute GVH disease
0.020 Biomarker disease BEFREE Treatment of primary human and murine T cells with TIP in vitro resulted in the secretion of IFN-gamma, TNF-alpha, and IL-10, whereas in vivo TIP had a protective effect in a mouse acute graft-versus-host disease (GVHD) model. 12598909 2003
CUI: C0029882
Disease: Otitis Media
Otitis Media
0.010 Biomarker disease BEFREE Grading TIP is a valid method for accurate diagnosis of pediatric otitis media and can predict the tympanometry result with high statistical significance. 31202036 2019
CUI: C0039538
Disease: Teratoma
Teratoma
0.010 GeneticVariation disease BEFREE Our data suggest that approximately half of the patient with cisplatin-refractory or relapsed GCT salvaged with TIP or TICE chemotherapy and evidence of residual disease are at risk of harboring either viable GCT or teratoma. 30296502 2019
CUI: C0220620
Disease: Gastrointestinal Carcinoid Tumor
Gastrointestinal Carcinoid Tumor
0.010 GeneticVariation disease BEFREE Our data suggest that approximately half of the patient with cisplatin-refractory or relapsed GCT salvaged with TIP or TICE chemotherapy and evidence of residual disease are at risk of harboring either viable GCT or teratoma. 30296502 2019
CUI: C0431399
Disease: Familial aplasia of the vermis
Familial aplasia of the vermis
0.010 Biomarker disease BEFREE We show that another Joubert syndrome-associated cilia tip protein, CSPP1, interacts with CEP104 at microtubules for the regulation of axoneme length. 31412255 2019
CUI: C0948908
Disease: Nephrotoxic serum nephritis
Nephrotoxic serum nephritis
0.010 Biomarker disease BEFREE The TNF-derived TIP peptide activates the epithelial sodium channel and ameliorates experimental nephrotoxic serum nephritis. 30905471 2019
CUI: C1368898
Disease: Adult Teratoma
Adult Teratoma
0.010 GeneticVariation disease BEFREE Our data suggest that approximately half of the patient with cisplatin-refractory or relapsed GCT salvaged with TIP or TICE chemotherapy and evidence of residual disease are at risk of harboring either viable GCT or teratoma. 30296502 2019
CUI: C2347762
Disease: Childhood Teratoma
Childhood Teratoma
0.010 GeneticVariation disease BEFREE Our data suggest that approximately half of the patient with cisplatin-refractory or relapsed GCT salvaged with TIP or TICE chemotherapy and evidence of residual disease are at risk of harboring either viable GCT or teratoma. 30296502 2019
CUI: C2827407
Disease: Infectious Otitis Media
Infectious Otitis Media
0.010 Biomarker disease BEFREE Grading TIP is a valid method for accurate diagnosis of pediatric otitis media and can predict the tympanometry result with high statistical significance. 31202036 2019
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.010 Biomarker group BEFREE We expect TIP to be useful in a large number of emerging cancer immunity studies and development of effective immunotherapy biomarkers. 30154154 2018
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.010 Biomarker phenotype BEFREE The E3 Ubiquitin Ligase HectD1 Suppresses EMT and Metastasis by Targeting the +TIP ACF7 for Degradation. 29386124 2018
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.010 Biomarker group BEFREE We developed a user-friendly one-stop shop web tool called TIP to comprehensively resolve tumor immunophenotype. 30154154 2018
CUI: C0234233
Disease: Sore to touch
Sore to touch
0.010 Biomarker phenotype BEFREE The muscle TIP had superior values of subjective tenderness, juiciness, and slight off-flavor intensity when compared to all other muscles.The TIP and SUB were similar in WBSF. 28942340 2018
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.010 Biomarker group BEFREE We expect TIP to be useful in a large number of emerging cancer immunity studies and development of effective immunotherapy biomarkers. 30154154 2018
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast
0.010 Biomarker disease BEFREE The interaction between RUVBL1 and ITFG1 is required for breast cancer cell collective invasion and progression. 28341484 2017
CUI: C0010674
Disease: Cystic Fibrosis
Cystic Fibrosis
0.010 Biomarker disease BEFREE Inhaled tobramycin, used to manage P. aeruginosa infection in CF patients, is available as powder (tobramycin inhalation powder, TIP) and solution (tobramycin inhalation solution, TIS). 28643178 2017
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.010 Biomarker disease BEFREE The interaction between RUVBL1 and ITFG1 is required for breast cancer cell collective invasion and progression. 28341484 2017
CUI: C0853879
Disease: Invasive carcinoma of breast
Invasive carcinoma of breast
0.010 Biomarker disease BEFREE Targeting collective invasion promoted by RUVBL1-ITFG1 complex provides a novel therapeutic strategy to improve the prognosis of invasive breast cancer. 28341484 2017
CUI: C0030499
Disease: Parasitic Diseases
Parasitic Diseases
0.010 Biomarker group BEFREE This study characterized the PfTip protein, a homolog of the human T‑cell immunomodulatory protein, and examined its function in preventing parasite infection. 26935027 2016
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.010 AlteredExpression group BEFREE Microtubule plus‑end‑binding protein (+TIP) EB1 has been shown to be upregulated in breast cancer cells and promote breast tumor growth in vivo. 25310526 2015